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术前疼痛管理方案与微创肺切除术后阿片类药物处方量的减少相关。

Pre-emptive pain management program is associated with reduction of opioid prescription after minimally invasive pulmonary resection.

作者信息

Del Calvo Haydee, Nguyen Duc T, Meisenbach Leonora M, Chihara Ray, Chan Edward Y, Graviss Edward A, Kim Min P

机构信息

Division of Thoracic Surgery, Department of Surgery, Houston Methodist Hospital, Houston, TX, USA.

Department of Pathology and Genomic Medicine, Houston Methodist Hospital, Houston, TX, USA.

出版信息

J Thorac Dis. 2020 May;12(5):1982-1990. doi: 10.21037/jtd-20-431.

Abstract

BACKGROUND

We developed and implemented a pre-emptive pain management program wherein providers agreed to have non-opioid pain medication as a standard pain management strategy at discharge accompanied by patient education about the program.

METHODS

A retrospective case-control study of prospectively collected data of patients who underwent minimally invasive pulmonary resection. We compared the outcomes among patients who were managed with pre-emptive pain management program with enhanced recovery after surgery (Pre-emptive), enhanced recovery program after surgery alone (ERAS) and standard care (control).

RESULTS

Of the 443 patients, 132 patients (30%) were in the pre-emptive pain management group, 90 (20%) patients were in the ERAS only group and 221 (50%) in the control group. There were significantly fewer complications (15.9% 23.3% 38%, P<0.001), shorter median length of hospital stay (2 3 3 days, P<0.001), lower 30-day readmission rates (2.3% 3.3% 11.3%, P=0.002), and fewer opioid prescriptions at discharge (17.4% 76.7% 83.7%, P<0.001) in the pre-emptive pain management group compared to the ERAS and control groups. Multivariate logistic regression analyses showed that the pre-emptive pain management program (OR 0.06; 95% CI, 0.03, 0.11, P<0.001) and robotic surgery (OR 0.52; 95% CI, 0.3, 0.88, P=0.02) were associated with lower odds of patients being discharged to home with opioid prescriptions. The median pain score in the pre-emptive pain group at 30 days after surgery was 1.5 on a pain scale of 1-10.

CONCLUSIONS

The pre-emptive pain management program was associated with a decrease in opioid prescriptions after elective pulmonary resections. Successful implementation of this program can lead to significant decreases in the amount of prescription opioids in the community.

摘要

背景

我们制定并实施了一项前瞻性疼痛管理计划,在此计划中,医疗服务提供者同意将非阿片类止痛药物作为出院时的标准疼痛管理策略,并对患者进行该计划相关的教育。

方法

对前瞻性收集的接受微创肺切除术患者的数据进行回顾性病例对照研究。我们比较了接受前瞻性疼痛管理计划并联合术后加速康复(前瞻性组)、单纯术后加速康复计划(ERAS组)和标准护理(对照组)的患者的结局。

结果

在443例患者中,132例患者(30%)在前瞻性疼痛管理组,90例(20%)患者仅在ERAS组,221例(50%)在对照组。与ERAS组和对照组相比,前瞻性疼痛管理组的并发症显著更少(15.9% 对23.3% 对38%,P<0.001),中位住院时间更短(2天 对3天 对3天,P<0.001),30天再入院率更低(2.3% 对3.3% 对11.3%,P=0.002),出院时的阿片类药物处方更少(17.4% 对76.7% 对83.7%,P<0.001)。多因素逻辑回归分析显示,前瞻性疼痛管理计划(比值比0.06;95%置信区间,0.03,0.11,P<0.001)和机器人手术(比值比0.52;95%置信区间,0.3,0.88,P=0.02)与患者出院时带阿片类药物处方的较低几率相关。前瞻性疼痛组术后30天的中位疼痛评分在1-10分的疼痛量表上为1.5分。

结论

前瞻性疼痛管理计划与择期肺切除术后阿片类药物处方的减少相关联。该计划的成功实施可导致社区中处方阿片类药物数量的显著减少。

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