Suppr超能文献

附有、未附以及没有吸入器技术指导工具,以优化成年哮喘患者使用压力定量吸入器的能力、哮喘控制情况及生活质量。

ATTACHED, DETACHED and WITHOUT inhaler technique coaching tools to optimize pMDI use competence, asthma control and quality-of-life in asthmatic adults.

作者信息

Ammari Wesam G, Obeidat Nathir M, Anani Abed Rahman, AlKalbani Reem J, Sanders Mark

机构信息

Pharmacological and Diagnostic Research Centre (PDRC), Faculty of Pharmacy, Al-Ahliyya Amman University, Amman, Jordan.

Faculty of Medicine and Jordan University Hospital, University of Jordan, Amman, Jordan.

出版信息

J Thorac Dis. 2020 May;12(5):2415-2425. doi: 10.21037/jtd.2020.03.50.

Abstract

BACKGROUND

Poor pressurized metered dose inhaler (pMDI) technique is prevalent, which will diminish treatment gains. In a two-visit study, two novel pMDI training devices with feedback mechanisms; Trainhaler (THR) and Flo-Tone CR (FTCR), were evaluated alongside the traditional verbal inhaler training (VT) in asthma outpatients.

METHODS

On visit 1, 18-60 year-old asthmatics with incorrect pMDI use [including peak inhalation flow (PIF) >60 L/min] signed consent and baseline pMDI technique, lung function, asthma control and quality-of-life were measured. Participants were randomized to receive pMDI technique training using VT, THR or FTCR. One hour post-training, the pMDI coordination and PIF were re-assessed. The THR and FTCR patients were given their assigned tools to take home to facilitate regular training. All outcomes were re-evaluated 6-8 weeks later (visit 2).

RESULTS

Ninety-two asthmatics completed visit 1 (46 attended visit 2). Pre-training, 61.3% (VT), 61.5% (THR) and 65.0% (FTCR) patients similarly made ≥2 pMDI errors with mean PIFs 175.2, 187.1 and 158.9 L/min, respectively. pMDI use was significantly improved 1 h post-training. The subjects that completed visit 2 had significantly, yet equally, maintained the improved inhaler use; only 28.0% (VT), 26.2% (THR) and 21.7% (FTCR) patients made ≥2 pMDI errors with PIF improvements; 115.3, 94.6 and 96.1 L/min, respectively. Clinical outcomes remained comparable.

CONCLUSIONS

VT improves the overall pMDI technique, however patients gradually forget their VT. The THR and FTCR devices are retained by the patients as their self-monitoring, all-time personal trainers that boost and maintain their VT between routine clinic visits.

摘要

背景

压力定量吸入器(pMDI)使用技术欠佳的情况很普遍,这会降低治疗效果。在一项分两次就诊的研究中,对两种带有反馈机制的新型pMDI训练装置;Trainhaler(THR)和Flo-Tone CR(FTCR),与传统的口头吸入器训练(VT)一起在哮喘门诊患者中进行了评估。

方法

在第一次就诊时,年龄在18至60岁、pMDI使用不正确[包括最大吸入流速(PIF)>60升/分钟]的哮喘患者签署知情同意书,并测量其基线pMDI技术、肺功能、哮喘控制情况和生活质量。参与者被随机分配接受使用VT、THR或FTCR的pMDI技术培训。训练后1小时,重新评估pMDI协调性和PIF。给使用THR和FTCR的患者发放他们所分配的工具带回家,以方便进行定期训练。6至8周后(第二次就诊)对所有结果进行重新评估。

结果

92名哮喘患者完成了第一次就诊(46名参加了第二次就诊)。训练前,61.3%(VT组)、61.5%(THR组)和65.0%(FTCR组)的患者同样出现了≥2次pMDI使用错误,平均PIF分别为175.2、187.1和158.9升/分钟。训练后1小时,pMDI的使用情况有显著改善。完成第二次就诊的受试者显著且同等程度地保持了吸入器使用的改善;只有28.0%(VT组)、26.2%(THR组)和21.7%(FTCR组)的患者出现了≥2次pMDI使用错误,PIF分别提高了115.3、94.6和96.1升/分钟。临床结果仍然相当。

结论

VT可改善整体pMDI技术,然而患者会逐渐忘记他们所接受的VT训练内容。THR和FTCR装置被患者留存下来,作为他们的自我监测工具和随时可用的私人训练器,在常规门诊就诊期间强化并维持他们的VT训练效果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ce2/7330348/bd4ab5dc513f/jtd-12-05-2415-f1.jpg

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验