O'Connor Kyle P, Pelargos Panayiotis E, Milton Camille K, Peterson Jo Elle G, Bohnstedt Bradley
Neurosurgery, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Pathology, University of Oklahoma Health Sciences Center, Oklahoma City, USA.
Cureus. 2020 Jun 8;12(6):e8512. doi: 10.7759/cureus.8512.
is a fungus that commonly invades the central nervous system. While the choroid plexus, the site of the blood-cerebrospinal fluid barrier, serves as one potential entry point for the pathogen, disease involvement of the choroid plexus itself remains a very rare manifestation of infection. In cases in which choroid plexus involvement blocks cerebrospinal fluid flow, obstructive hydrocephalus may occur. Here we report the case of a 63-year-old woman who presented with choroid plexitis causing obstructive hydrocephalus at the foramen of Monro. Endoscopic biopsy confirmed and the patient was successfully treated with amphotericin, flucytosine, and fluconazole. With proper recognition and treatment of this pathology, patients can fully recover from this condition.
是一种常见侵犯中枢神经系统的真菌。虽然血脑屏障所在部位脉络丛是病原体的一个潜在侵入点，但脉络丛本身受累的疾病仍是感染的一种非常罕见的表现形式。在脉络丛受累导致脑脊液流动受阻的情况下，可能会发生梗阻性脑积水。在此，我们报告一例63岁女性病例，该患者因脉络丛炎导致门罗孔处梗阻性脑积水。内镜活检得以确诊，患者接受两性霉素、氟胞嘧啶和氟康唑治疗后成功康复。通过对这种病理情况的正确识别和治疗，患者可以完全康复。
