Biomedical Sciences Department, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.
Front Cell Infect Microbiol. 2020 Jun 23;10:214. doi: 10.3389/fcimb.2020.00214. eCollection 2020.
Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host-pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.
由于果蝇和哺乳动物之间存在遗传相似性和保守途径，因此使用该模型作为揭示感染和疾病进展新机制的平台是合理的，并且已经得到广泛应用。深入了解宿主-病原体相互作用，并确定宿主防御和病原体毒力中涉及的主要因素，是在高等生物（包括人类）中建立传染病防控新策略的基础。
