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作为宿主-病原体相互作用研究中的模式生物。

as a Model Organism in Host-Pathogen Interaction Studies.

机构信息

Biomedical Sciences Department, College of Health Sciences, QU Health, Qatar University, Doha, Qatar.

出版信息

Front Cell Infect Microbiol. 2020 Jun 23;10:214. doi: 10.3389/fcimb.2020.00214. eCollection 2020.

Abstract

Owing to the genetic similarities and conserved pathways between a fruit fly and mammals, the use of the model as a platform to unveil novel mechanisms of infection and disease progression has been justified and widely instigated. Gaining proper insight into host-pathogen interactions and identifying chief factors involved in host defense and pathogen virulence in serves as a foundation to establish novel strategies for infectious disease prevention and control in higher organisms, including humans.

摘要

由于果蝇和哺乳动物之间存在遗传相似性和保守途径,因此使用该模型作为揭示感染和疾病进展新机制的平台是合理的,并且已经得到广泛应用。深入了解宿主-病原体相互作用,并确定宿主防御和病原体毒力中涉及的主要因素,是在高等生物(包括人类)中建立传染病防控新策略的基础。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9290/7324642/ffb269b5a9ba/fcimb-10-00214-g0001.jpg

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