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基于银纳米粒子的新型抗病毒和抗菌药物。

New Antivirals and Antibacterials Based on Silver Nanoparticles.

机构信息

Istituto per lo Studio dei Materiali Nanostrutturati, CNR, via U. La Malfa 153, 90146, Palermo, Italy.

Department Chemical Engineering, Materials and Biotechnology The Center for Radical Reactions, Ariel University, Jerusalem, Israel.

出版信息

ChemMedChem. 2020 Sep 3;15(17):1619-1623. doi: 10.1002/cmdc.202000390. Epub 2020 Jul 30.

DOI:10.1002/cmdc.202000390
PMID:32657536
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7404954/
Abstract

The rediscovery of the medical uses of silver provides another noticeable example, this time at the interface of chemistry and medicine, of the real (and nonlinear) progress of scientific research. Several new silver-based antimicrobial products have thus been commercialized in the last two decades. Next-generation antibacterials and antivirals of broad scope, low toxicity and affordable cost, we argue in this study, will be based on microencapsulated Ag nanoparticles.

摘要

银在医学上的新用途的重新发现,为我们提供了另一个显著的例子,这一次是在化学和医学的交叉点上,说明了科学研究的真正(而非线性)进展。在过去的二十年中,因此已经有几种基于银的新型抗菌产品实现了商业化。我们在这项研究中提出,具有广谱、低毒性和可负担成本的下一代抗菌和抗病毒药物将基于微囊化的银纳米粒子。

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本文引用的文献

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Antimicrobial Activity of Silver-Treated Bacteria against other Multi-Drug Resistant Pathogens in Their Environment.经银处理的细菌对其环境中其他多重耐药病原体的抗菌活性。
Antibiotics (Basel). 2020 Apr 15;9(4):181. doi: 10.3390/antibiotics9040181.
2
SilverSil: A New Class of Antibacterial Materials of Broad Scope.银硅:一类新型的广谱抗菌材料。
ChemistryOpen. 2020 Apr 9;9(4):459-463. doi: 10.1002/open.202000016. eCollection 2020 Apr.
3
Inhibition of Biofilm Formation on Medical and Environmental Surfaces by Silver Nanoparticles.银纳米粒子抑制医用和环境表面生物膜的形成。
ACS Appl Mater Interfaces. 2020 May 13;12(19):21183-21191. doi: 10.1021/acsami.9b20708. Epub 2020 Jan 16.
4
Optimization of silver nanoparticle synthesis by chemical reduction and evaluation of its antimicrobial and toxic activity.通过化学还原法优化银纳米颗粒的合成及其抗菌和毒性活性评估。
Biomater Res. 2019 Dec 19;23:27. doi: 10.1186/s40824-019-0173-y. eCollection 2019.
5
Antimicrobial Activity of Biosynthesized Silver Nanoparticles Decorated Silica Nanoparticles.生物合成的二氧化硅纳米颗粒负载银纳米颗粒的抗菌活性
Indian J Microbiol. 2019 Sep;59(3):379-382. doi: 10.1007/s12088-019-00812-2. Epub 2019 Jun 10.
6
Using a Chemical Genetic Screen to Enhance Our Understanding of the Antibacterial Properties of Silver.利用化学遗传学筛选增进我们对银抗菌特性的理解。
Genes (Basel). 2018 Jul 6;9(7):344. doi: 10.3390/genes9070344.
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Do physico-chemical properties of silver nanoparticles decide their interaction with biological media and bactericidal action? A review.银纳米粒子的物理化学性质决定了它们与生物介质的相互作用和杀菌作用吗?一篇综述。
Mater Sci Eng C Mater Biol Appl. 2018 Sep 1;90:739-749. doi: 10.1016/j.msec.2018.04.093. Epub 2018 May 1.
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Recent advances on silver nanoparticle and biopolymer-based biomaterials for wound healing applications.基于银纳米粒子和生物聚合物的生物材料在创伤愈合应用中的最新进展。
Int J Biol Macromol. 2018 Aug;115:165-175. doi: 10.1016/j.ijbiomac.2018.04.003. Epub 2018 Apr 5.
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Evidence for silver in wound care - meta-analysis of clinical studies from 2000-2015.伤口护理中银的证据——2000年至2015年临床研究的荟萃分析。
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