Department of Molecular Reproduction, Development and Genetics; Indian Institute of Science, Bangalore, India.
Int J Dev Biol. 2020;64(1-2-3):167-173. doi: 10.1387/ijdb.190333un.
Myogenesis is a complex multifactorial process leading to the formation of the adult muscle. An amalgamation of autonomous processes including myoblast fusion and myofibrillogenesis, as well as non-autonomous processes, such as innervations from neurons and precise connections with attachment sites, are responsible for successful development and function of muscles. In this review, we describe the development of the indirect flight muscles (IFMs) in Drosophila melanogaster, and highlight the use of the IFMs as a model for studying muscle development and disease, based on recent studies on the development and function of IFMs.
成肌作用是一个复杂的多因素过程，导致成年肌肉的形成。一系列自主过程，包括成肌细胞融合和肌原纤维发生，以及非自主过程，如神经元的神经支配和与附着位点的精确连接，负责肌肉的成功发育和功能。在这篇综述中，我们描述了果蝇的间接飞行肌肉（IFM）的发育，并基于最近关于 IFM 的发育和功能的研究，强调了将 IFM 用作研究肌肉发育和疾病的模型。
