Montorio Daniela, Cennamo Gilda, Menna Feliciana, Donna Piero, Napolitano Pasquale, Breve Maria Angelica, Fiore Ugo, Cennamo Giovanni, Rosa Nicola
Department of Neurosciences, Reproductive Sciences and Dentistry, University of Naples Federico II, Naples, Italy.
Eye Clinic, Public Health Department, University of Naples Federico II, Naples, Italy.
J Biophotonics. 2020 Oct;13(10):e202000138. doi: 10.1002/jbio.202000138. Epub 2020 Aug 7.
The aim of this study is to evaluate corneal epithelial thickness (CET), corneal densitometry (CD) in 84 myopic eyes (57 patients) more than 22 years after photorefractive keratectomy, using anterior segment-optical coherence tomography (AS-OCT) and Scheimpflug imaging system. The CET was significantly higher in all operated eyes than in unoperated eyes in central sector. A statistically significant increase in CD in corneal anterior layer of central sector was shown in groups of operated eyes with greater ablation depth respect to unoperated eyes. While there was no significant difference in CD between the operated eyes groups with lower ablation depth and unoperated eyes. A significant trend toward higher values in anterior CD with deeper ablations in central sector was found. These noninvasive imaging techniques allow to better understand the corneal remodeling process after photoablation and to monitor the patients over time.
本研究的目的是使用眼前节光学相干断层扫描（AS-OCT）和Scheimpflug成像系统，评估84只近视眼睛（57例患者）在屈光性角膜切削术后22年以上的角膜上皮厚度（CET）和角膜密度测定（CD）。所有手术眼的中央区CET均显著高于未手术眼。与未手术眼相比，消融深度较大的手术眼组中央区角膜前层的CD有统计学意义的增加。而消融深度较小的手术眼组与未手术眼之间的CD无显著差异。发现中央区消融越深，前层CD值越高的显著趋势。这些非侵入性成像技术有助于更好地理解光消融后的角膜重塑过程，并长期监测患者。
