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2
Optimization of submerged culture conditions involving a developed fine powder solid seed for exopolysaccharide production by the medicinal mushroom .通过药用蘑菇利用已开发的细粉固体种子进行胞外多糖生产的深层培养条件优化。
Food Sci Biotechnol. 2018 Dec 12;28(4):1135-1145. doi: 10.1007/s10068-018-0536-5. eCollection 2019 Aug.
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Potential immunomodulatory activities of a lectin from the mushroom Latiporus sulphureus.硫色多孔菌凝集素的潜在免疫调节活性。
Int J Biol Macromol. 2019 Jun 1;130:399-406. doi: 10.1016/j.ijbiomac.2019.02.150. Epub 2019 Feb 26.
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Drug Discov Today. 2019 Jan;24(1):307-314. doi: 10.1016/j.drudis.2018.09.014. Epub 2018 Sep 25.
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Enhanced active extracellular polysaccharide production from Ganoderma formosanum using computational modeling.利用计算建模技术提高灵芝胞外多糖的产量。
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Matsutakone and Matsutoic Acid, Two (Nor)steroids with Unusual Skeletons from the Edible Mushroom Tricholoma matsutake.松塔酮和松塔烯酸,两种来自可食用蘑菇松露的具有不寻常骨架的(降)甾体。
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关于蘑菇的深层培养及其生物活性代谢产物的批判性综述。

A critical review on submerged production of mushroom and their bioactive metabolites.

作者信息

Dudekula Umera Tasleem, Doriya Kruthi, Devarai Santhosh Kumar

机构信息

Industrial Bioprocess and BioProspecting Laboratory (IBBL), Department of Chemical Engineering, Indian Institute of Technology Hyderabad, Kandi, Sangareddy, Telangana State 502285 India.

出版信息

3 Biotech. 2020 Aug;10(8):337. doi: 10.1007/s13205-020-02333-y. Epub 2020 Jul 8.

DOI:10.1007/s13205-020-02333-y
PMID:32670737
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7343686/
Abstract

Mushrooms are ubiquitous in nature. Even though humankind has been consuming mushrooms for ages, their medicinal and nutraceutical properties are not used to its fullest potential in the present market. Edible mushrooms are not only a cheap and nutritious option to mitigate malnutrition, but they also produce effective biomass. Submerged fermentation (SmF) is not only a cost-effective method to produce biomass along with exquisite bioactive metabolites but it also reduces the chances of contamination and the time of production. Therefore, this study unveils the bioactive metabolites being produced by mushrooms. Moreover, it also showcases the recent advances in the areas of bio-active compounds and their judicious implementations in daily life and pharmaceutical industries. Moreover, there is a distinct lack in utilizing the potential benefits of bioactive compounds from mushroom unless in vivo and in vitro studies are demonstrated.

摘要

蘑菇在自然界中无处不在。尽管人类食用蘑菇已有很长时间,但在当前市场上,它们的药用和营养特性尚未得到充分利用。可食用蘑菇不仅是缓解营养不良的廉价且营养丰富的选择,而且还能产生有效的生物质。深层发酵(SmF)不仅是一种具有成本效益的生产生物质以及精致生物活性代谢物的方法,而且还减少了污染机会和生产时间。因此,本研究揭示了蘑菇产生的生物活性代谢物。此外,它还展示了生物活性化合物领域的最新进展及其在日常生活和制药行业中的明智应用。此外,除非进行体内和体外研究,否则在利用蘑菇生物活性化合物的潜在益处方面明显不足。