印度半湿润地区女性的农药风险与复发性流产
Pesticide Risk and Recurrent Pregnancy Loss in Females of Subhumid Region of India.
作者信息
Pandey Akancha, Jaiswar Shyam Pyari, Ansari Nasreen Ghazi, Deo Sujata, Sankhwar Pushplata, Pant Shriya, Upadhyay Sushil
机构信息
Department of Obstetrics and Gynecology, King Georg's Medical University, Lucknow, Uttar Pradesh, India.
Metal Analysis Laboratory, CSIR Indian Institute of Toxicology Research, Lucknow, Uttar Pradesh, India.
出版信息
Niger Med J. 2020 Mar-Apr;61(2):55-59. doi: 10.4103/nmj.NMJ_117_18. Epub 2020 May 7.
OBJECTIVE
The objective of this study is to determine the level of pesticides and their role in cases of recurrent pregnancy loss (RPL).
MATERIALS AND METHODS
This was designed as a case-control study. Gas chromatography was used to characterize the pesticide level in 70 cases and 70 controls. Case refers to women with RPL, whereas controls refer to women with full-term delivery.
RESULTS
A higher level of pesticide, namely beta-hexachlorocyclohexane, malathion, chlorpyrifos, and fenvalerate was found in the case group as compared to control group ( < 0.05).
CONCLUSIONS
The present study suggests that high exposure of pesticide (organochlorine and organophosphates) may increase the risk of RPL in females of the subhumid region of India.
目的
本研究的目的是确定农药水平及其在复发性流产（RPL）病例中的作用。
材料与方法
本研究设计为病例对照研究。采用气相色谱法对70例病例和70例对照者的农药水平进行测定。病例组指复发性流产的女性，对照组指足月分娩的女性。
结果
与对照组相比，病例组中农药β-六氯环己烷、马拉硫磷、毒死蜱和氰戊菊酯的水平更高（<0.05）。
结论
本研究表明，在印度半湿润地区，女性高暴露于农药（有机氯和有机磷）可能会增加复发性流产的风险。
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