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循环疫苗衍生脊髓灰质炎病毒:消灭脊髓灰质炎行动的威胁。

Circulating vaccine-derived poliovirus: a menace to the end game of polio eradication.

机构信息

PAP Rashidah Sa'adatul Bolkiah Institute of Health Sciences, Universiti Brunei Darussalam, Jalan Tungku Link, Gadong, BE1410, Brunei Darussalam.

Discipline of Pharmacy, School of Health Sciences, Faculty of Health, University of Canberra, Canberra, Australia.

出版信息

Global Health. 2020 Jul 16;16(1):63. doi: 10.1186/s12992-020-00594-z.

Abstract

The World Health Organisation Western Pacific Region countries were declared free of polio in 2000 until a polio outbreak involving 305 cases occurred in Indonesia in 2006. It was not until 2014 that the World Health Organisation South East Asia region was officially declared polio-free again. However, in February 2019, the Global Polio Eradication Initiative announced a new circulating vaccine-derived poliovirus outbreak in the Papua province of Indonesia. To make matter worse, the outbreak responses were tardy and led to transmission among migrating communities to other cities. The pressing regional issues of polio outbreak caused by circulating vaccine-derived poliovirus and use of oral polio vaccine have not been well presented. Our letter highlighted the suboptimal outbreak responses as well as the necessity of cross-border vaccination to curb continued poliovirus transmission.

摘要

世界卫生组织西太平洋地区国家在 2000 年宣布消灭了脊髓灰质炎,直到 2006 年印度尼西亚爆发了涉及 305 例的脊髓灰质炎疫情。直到 2014 年,世界卫生组织东南亚地区才再次被宣布无脊髓灰质炎。然而,2019 年 2 月,全球根除脊髓灰质炎行动宣布印度尼西亚巴布亚省出现新的循环疫苗衍生脊髓灰质炎病毒疫情。更糟糕的是,疫情应对行动迟缓,导致迁徙社区向其他城市传播。循环疫苗衍生脊髓灰质炎病毒引起的脊髓灰质炎爆发和使用口服脊髓灰质炎疫苗这两个紧迫的区域性问题没有得到很好的呈现。我们的信函强调了疫情应对不佳以及跨境接种疫苗以遏制持续脊髓灰质炎病毒传播的必要性。

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