Perez-Puyana Victor, Jiménez-Rosado Mercedes, Romero Alberto, Guerrero Antonio
Departamento de Ingeniería Química, Facultad de Química, Universidad de Sevilla, 41012 Sevilla, Spain.
Departamento de Ingeniería Química, Escuela Politécnica Superior, Universidad de Sevilla, 41011 Sevilla, Spain.
Polymers (Basel). 2020 Jul 15;12(7):1566. doi: 10.3390/polym12071566.
Biomaterials have been used since ancient times. However, it was not until the late 1960s when their development prospered, increasing the research on them. In recent years, the study of biomaterials has focused mainly on tissue regeneration, requiring a biomaterial that can support cells during their growth and fulfill the function of the replaced tissue until its regeneration. These materials, called scaffolds, have been developed with a wide variety of materials and processes, with the polymer ones being the most advanced. For this reason, the need arises for a review that compiles the techniques most used in the development of polymer-based scaffolds. This review has focused on three of the most used techniques: freeze-drying, electrospinning and 3D printing, focusing on current and future trends. In addition, the advantages and disadvantages of each of them have been compared.
生物材料自古以来就被使用。然而，直到20世纪60年代末它们的发展才繁荣起来，对其研究也随之增加。近年来，生物材料的研究主要集中在组织再生方面，这就需要一种生物材料，它能够在细胞生长过程中支持细胞，并在被替换组织再生之前履行其功能。这些材料被称为支架，通过各种各样的材料和工艺开发而成，其中聚合物材料最为先进。因此，有必要进行一篇综述，汇编聚合物基支架开发中最常用的技术。本综述聚焦于三种最常用的技术：冷冻干燥、静电纺丝和3D打印，重点关注当前和未来的趋势。此外，还比较了它们各自的优缺点。
Zotero 插件
