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白内障患者角膜生物力学与共焦显微镜的相关性。

Correlations between corneal biomechanics and specular microscopy in patient with cataract.

机构信息

Department of Ophthalmology, University Emergency Hospital, Bucharest, Romania.

"Carol Davila" University of Medicine and Pharmacy, Bucharest, Romania.

出版信息

Rom J Ophthalmol. 2020 Apr-Jun;64(2):132-145.

Abstract

This study aimed to analyze the connection between corneal biomechanics (corneal hysteresis, CH) and endothelial cell density of cornea (mean endothelial cell density, MCD) in patients diagnosed with cataract. This retrospective, observational study was performed in the Ophthalmology Clinic of the University Emergency Hospital in Bucharest. Of 60 patients (120 eyes) with cataract, who were included in this study, we analyzed the CH values obtained using with the Ocular Response Analyzer (ORA) and the MCD values obtained using the specular microscopy. The study groups comprised both men and women with ages ranging from 45 to 63 years. Patients were divided into three study groups according to CH values. In each batch, the CH values obtained with the Ocular Response Analyzer (ORA) were correlated with age, gender and MCD, then the subgroups were compared. All the data gathered showed no correlation to be statistically significant regarding the biomechanical properties of the cornea and the corneal endothelial cell density in patients with cataract.

摘要

本研究旨在分析白内障患者角膜生物力学(角膜滞后,CH)与角膜内皮细胞密度(平均内皮细胞密度,MCD)之间的关系。这项回顾性观察研究在布加勒斯特大学急诊医院的眼科诊所进行。在这项研究中,我们分析了 60 名(120 只眼)白内障患者使用眼反应分析仪(ORA)获得的 CH 值和使用共焦显微镜获得的 MCD 值。研究组包括年龄在 45 岁至 63 岁之间的男性和女性患者。根据 CH 值将患者分为三组。在每一批中,都将使用眼反应分析仪(ORA)获得的 CH 值与年龄、性别和 MCD 相关联,然后对亚组进行比较。所有收集的数据均显示,在白内障患者的角膜生物力学特性和角膜内皮细胞密度方面,没有相关性具有统计学意义。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b5c4/7339691/8d9bad6240c9/RomJOphthalmol-64-132-g001.jpg

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