一般人群中肠胃炎的决定因素和风险因素，2014 年至 2017 年法国的一项基于网络的队列研究。
Determinants and risk factors of gastroenteritis in the general population, a web-based cohort between 2014 and 2017 in France.
机构信息
Sorbonne Université, INSERM, Institut Pierre Louis d'épidémiologie et de Santé Publique, IPLESP, F75012, Paris, France.
Department of Family Medicine, Faculté de Médecine, Université Paris Descartes, Paris, France.
出版信息
BMC Public Health. 2020 Jul 21;20(1):1146. doi: 10.1186/s12889-020-09212-4.
BACKGROUND
Although it is rarely fatal in developed countries, acute gastroenteritis (AGE) still induces significant morbidity and economic costs. The objective of this study was to identify factors associated with AGE in winter in the general population.
METHODS
A prospective study was performed during winter seasons from 2014 to 2015 to 2016-2017. Participants filled an inclusion survey and reported weekly data on acute symptoms. Factors associated with having at least one AGE episode per winter season were analyzed using the generalized estimating equations (GEE) approach.
RESULTS
They were 13,974 participants included in the study over the three seasons. On average, 8.1% of participants declared at least one AGE episode during a winter season. People over 60 declared fewer AGE episodes (adjusted OR (aOR) = 0.76, 95% CI [0.64; 0.89]) compared to individuals between 15 and 60 years old, as well as children between 10 and 15 (aOR = 0.60 [0.37; 0.98]). Overweight (aOR = 1.25 [1.07; 1.45]) and obese (aOR = 1.47 [1.19; 1.81]) individuals, those having frequent cold (aOR = 1.63 [1.37; 1.94]) and those with at least one chronic condition (aOR = 1.35 [1.16; 1.58]) had more AGE episodes. Living alone was associated with a higher AGE episode rate (aOR = 1.31 [1.09; 1.59]), as well as having pets at home (aOR = 1.23 [1.08; 1.41]).
CONCLUSIONS
Having a better knowledge of AGE determinants will be useful to adapt public health prevention messages.
背景
在发达国家，急性肠胃炎（AGE）虽然很少致命，但仍会导致较高的发病率和经济成本。本研究旨在确定普通人群冬季患 AGE 的相关因素。
方法
本前瞻性研究于 2014 年至 2015 年冬季季节以及 2016 年至 2017 年冬季季节进行。参与者填写了一份纳入调查，并按周报告急性症状数据。使用广义估计方程（GEE）方法分析与每个冬季季节至少发生一次 AGE 发作相关的因素。
结果
在三个季节中，共纳入了 13974 名参与者。平均而言，8.1%的参与者在一个冬季季节至少报告了一次 AGE 发作。与 15-60 岁之间的个体以及 10-15 岁的儿童相比，60 岁以上的人群报告的 AGE 发作次数较少（调整后的比值比[aOR] = 0.76，95%CI [0.64; 0.89]）。超重（aOR = 1.25 [1.07; 1.45]）和肥胖（aOR = 1.47 [1.19; 1.81]）人群、经常感冒（aOR = 1.63 [1.37; 1.94]）以及至少有一种慢性疾病（aOR = 1.35 [1.16; 1.58]）的人群 AGE 发作次数更多。独居（aOR = 1.31 [1.09; 1.59]）和家中有宠物（aOR = 1.23 [1.08; 1.41]）与更高的 AGE 发作率相关。
结论
更好地了解 AGE 的决定因素将有助于调整公共卫生预防信息。
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