Duinkerke S J, Gabreëls F J, Boerbooms A M, Kok J C, Renier W O
Clin Neurol Neurosurg. 1983;85(4):225-30. doi: 10.1016/0303-8467(83)90072-0.
The central nervous system (CNS) is frequently affected by systemic lupus erythematosus (SLE). Other causes, especially infection, may also originate CNS disease in SLE patients. Our findings indicate that measurement of lactic acid and pyruvic acid in cerebrospinal fluid (CSF) may be of help in separating inactive CNS-SLE from active CNS-SLE. Also it may be of help in differentiating sterile meningitis caused by SLE from bacterial meningitis. Because of the special risk on tuberculous and fungal infections in SLE patients, also some findings concerning these specific forms of meningitis are given.
中枢神经系统（CNS）常受系统性红斑狼疮（SLE）影响。其他病因，尤其是感染，也可能在SLE患者中引发中枢神经系统疾病。我们的研究结果表明，测量脑脊液（CSF）中的乳酸和丙酮酸可能有助于区分非活动性中枢神经系统SLE与活动性中枢神经系统SLE。此外，它可能有助于鉴别由SLE引起的无菌性脑膜炎与细菌性脑膜炎。鉴于SLE患者存在结核和真菌感染的特殊风险，本文还给出了有关这些特定类型脑膜炎的一些研究结果。
