Im Justin, Balasubramanian Ruchita, Ouedraogo Moussa, Wandji Nana Lady Rosny, Mogeni Ondari D, Jeon Hyon Jin, van Pomeren Tayma, Haselbeck Andrea, Lim Jacqueline Kyungah, Prifti Kristi, Baker Stephen, Meyer Christian G, Kim Jerome H, Clemens John D, Marks Florian, Soura Abdramane Bassiahi
International Vaccine Institute, Seoul, Republic of Korea.
Princeton University, Princeton, NJ, USA.
Heliyon. 2020 Jul 14;6(7):e04389. doi: 10.1016/j.heliyon.2020.e04389. eCollection 2020 Jul.
Dengue is prevalent in as many as 128 countries with more than 100 million clinical episodes reported annually and four billion people estimated to be at risk. While dengue fever is systematically diagnosed in large parts of Asia and South America, the disease burden in Africa is less well investigated. This report describes two consecutive dengue outbreaks in Ouagadougou, Burkina Faso in 2016 and 2017.
Blood samples of febrile patients received at Schiphra laboratory in Ouagadougou, Burkina Faso, were screened for dengue infection using SD Bioline Dengue Duo rapid diagnostic test kits (Standard Diagnostics, Suwon, Republic of Korea).
A total of 1,397 and 1,882 cases were reported by a single laboratory in 2016 and 2017, respectively. Most cases were at least 15 years of age and the results corroborated reports from WHO indicating the circulation of three dengue virus serotypes in Burkina Faso.
This study complements data from other, simultaneously conducted surveillance efforts, and indicates that the dengue disease burden might be underestimated in sub-Saharan African nations. Dengue surveillance should be enhanced in African settings to determine the burden more accurately, and accelerated efforts towards a dengue vaccine should be put in place.
登革热在多达128个国家流行,每年报告的临床病例超过1亿例,估计有40亿人面临风险。虽然在亚洲和南美洲的大部分地区登革热已得到系统诊断,但非洲的疾病负担研究较少。本报告描述了2016年和2017年布基纳法索瓦加杜古连续两次登革热疫情。
在布基纳法索瓦加杜古的Schiphra实验室接收的发热患者血样,使用SD Bioline登革热双联快速诊断试剂盒(标准诊断公司,韩国水原)进行登革热感染筛查。
2016年和2017年,一个实验室分别报告了1397例和1882例病例。大多数病例年龄至少为15岁,结果证实了世界卫生组织的报告,表明布基纳法索有三种登革热病毒血清型在传播。
本研究补充了其他同时进行的监测工作的数据,并表明撒哈拉以南非洲国家的登革热疾病负担可能被低估。应加强非洲地区的登革热监测,以更准确地确定负担,并加快登革热疫苗的研发工作。