不同年龄 2 型糖尿病患者综合控制目标的实现情况。
The achievement of comprehensive control targets among type 2 diabetes mellitus patients of different ages.
机构信息
Department of Endocrinology and Metabolism, Geriatric Hospital of Nanjing Medical University, Nanjing, China.
Division of Geriatrics, Drum Tower Clinical Medical College of Nanjing Medical University, Nanjing, China.
出版信息
Aging (Albany NY). 2020 Jul 22;12(14):14066-14079. doi: 10.18632/aging.103358.
OBJECTIVE
To evaluate achievement of comprehensive controls among patients with type 2 diabetes mellitus (T2DM) in different age groups.
RESULTS
The elderly patients had higher control rates for BMI (44.36%), TC (50.83%) and LDL-C (48.27%) than those aged 60-80 years and younger patients (all <0.05). Multiple logistic regression revealed that elderly patients were more likely to achieve control targets for HbA1c (odd ratio (OR) = 2.19), TC (OR = 1.32), HDL-C (OR = 1.35), and TG (OR = 1.74) than younger patients. This effect was stronger in males (OR = 2.27; OR = 1.41; OR = 1.51; OR = 1.80). By contrast, elderly females were only more likely to achieve HbA1c < 7.0% (OR=1.88).
CONCLUSIONS
Our findings suggest that comprehensive control strategies still should be strengthened.
METHODS
A total of 3126 T2DM patients were included, and detected blood pressure (BP), body mass index (BMI), glycosylated hemoglobin (HbA1c), fasting plasma glucose (FPG), postprandial plasma glucose (PPG), total cholesterol (TC), low density lipoprotein cholesterol (LDL-C), triglycerides (TG), and high-density lipoprotein cholesterol (HDL-C). We divided patients into three age groups (<60, 60-80 and ≥ 80 years), to assess the differences in achieving the control targets.
目的
评估不同年龄组 2 型糖尿病（T2DM）患者综合控制的达标情况。
结果
老年患者的 BMI（44.36%）、TC（50.83%）和 LDL-C（48.27%）控制率均高于 60-80 岁和年轻患者（均<0.05）。多因素 logistic 回归显示，与年轻患者相比，老年患者更易达到 HbA1c（OR=2.19）、TC（OR=1.32）、HDL-C（OR=1.35）和 TG（OR=1.74）的控制目标。这种作用在男性中更强（OR=2.27；OR=1.41；OR=1.51；OR=1.80）。相比之下，老年女性仅更有可能达到 HbA1c<7.0%（OR=1.88）。
结论
我们的研究结果表明，综合控制策略仍需加强。
方法
共纳入 3126 例 T2DM 患者，检测血压（BP）、体重指数（BMI）、糖化血红蛋白（HbA1c）、空腹血糖（FPG）、餐后血糖（PPG）、总胆固醇（TC）、低密度脂蛋白胆固醇（LDL-C）、甘油三酯（TG）和高密度脂蛋白胆固醇（HDL-C）。我们将患者分为三组（<60、60-80 和≥80 岁），以评估达到控制目标的差异。
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