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新型冠状病毒的流行病学和临床特征:来自巴基斯坦卡拉奇东部的一项回顾性研究

Epidemiological and Clinical Features of SARS-CoV-2: A Retrospective Study from East Karachi, Pakistan.

作者信息

Tahir Shumaila, Tahir Syeda Anjala, Bin Arif Taha, Majid Bushra, Majid Zainab, Malik Farheen, Ahmed Ashfaque, Memon Arslan, Ahmed Jawad

机构信息

Internal Medicine, District Health Office, East Karachi, PAK.

Internal Medicine, Civil Hospital Karachi, Karachi, PAK.

出版信息

Cureus. 2020 Jun 17;12(6):e8679. doi: 10.7759/cureus.8679.

DOI:10.7759/cureus.8679
PMID:32699679
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7372194/
Abstract

Background Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has spread to almost every country on the globe, and each country is reporting the symptomatic presentation of their patients to give better insight into the various clinical presentations of SARS-CoV-2. However, the epidemiological literature from Pakistan is scanty. Methods We retrospectively analyzed data from 412 patients who were residents of East Karachi and tested positive for SARS-CoV-2 between February 26 to April 24, 2020. Patients' demographics, symptoms, travel and contact history, and outcomes were recorded. All statistical analysis was performed using the Statistical Package for the Social Sciences (SPSS) version 22 (IBM SPSS Statistics for Windows, IBM Corp, Armonk, NY). Results Most of the patients were male (64.6%), the majority (43.3%) belonging to the 21- to 40-year age group. Most of the patients (65.5%) were residents of Gulshan Iqbal. A total of 15.8% of the patients were admitted to the hospital, and 3.9% of patients expired. The three most common presenting symptoms were fever (74.8%), cough (60.4%), and flu (35.5%). The majority of patients (89.3%) gave a history of contact with SARS-CoV-2 patients. Conclusion The number of SARS-CoV-2 cases is rapidly increasing in Karachi, Pakistan. There is a need to educate the population about the most common sign and symptoms of the virus so that individuals can identify these symptoms and get themselves tested. The concerned authorities should devise an adequate and effective plan to flatten the infectivity curve.

摘要

背景 严重急性呼吸综合征冠状病毒2(SARS-CoV-2)已传播到全球几乎每个国家,每个国家都在报告其患者的症状表现,以便更好地了解SARS-CoV-2的各种临床表现。然而,来自巴基斯坦的流行病学文献很少。方法 我们回顾性分析了2020年2月26日至4月24日期间居住在东卡拉奇且SARS-CoV-2检测呈阳性的412例患者的数据。记录了患者的人口统计学信息、症状、旅行和接触史以及结局。所有统计分析均使用社会科学统计软件包(SPSS)22版(IBM SPSS Statistics for Windows,IBM公司,纽约州阿蒙克)进行。结果 大多数患者为男性(64.6%),大多数(43.3%)属于21至40岁年龄组。大多数患者(65.5%)居住在古勒山·伊克巴尔。共有15.8%的患者入院,3.9%的患者死亡。三种最常见的症状是发热(74.8%)、咳嗽(60.4%)和流感样症状(35.5%)。大多数患者(89.3%)有与SARS-CoV-2患者接触史。结论 在巴基斯坦卡拉奇,SARS-CoV-2病例数正在迅速增加。有必要对民众进行关于该病毒最常见体征和症状的教育,以便个人能够识别这些症状并进行检测。有关当局应制定一项充分有效的计划来平缓感染曲线。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6db/7372194/db408b424483/cureus-0012-00000008679-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6db/7372194/db408b424483/cureus-0012-00000008679-i01.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/b6db/7372194/db408b424483/cureus-0012-00000008679-i01.jpg

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