Symmons D P, Coppock J S, Bacon P A, Bresnihan B, Isenberg D A, Maddison P, McHugh N, Snaith M L, Zoma A S
Department of Rheumatology, University of Birmingham, Medical School.
Q J Med. 1988 Nov;69(259):927-37.
Five centres in Great Britain and the Republic of Ireland have collaborated to produce a computerized index of clinical disease activity in systemic lupus erythematosus, based on the principle of the physician's intention to treat. The index assesses separately eight organ-based systems. The index has proved quick and easy to use despite a comprehensive database and compares favourably with two other indices of disease activity. It has great potential for use in multicentre studies of disease outcome and new therapies in systemic lupus erythematosus.
英国和爱尔兰共和国的五个中心合作,基于医生的治疗意图原则,编制了一个系统性红斑狼疮临床疾病活动的计算机化索引。该索引分别评估八个基于器官的系统。尽管有一个全面的数据库,但该索引已被证明使用起来快速简便,并且与其他两个疾病活动指数相比具有优势。它在系统性红斑狼疮疾病结局和新疗法的多中心研究中具有巨大的应用潜力。