Department of Child and Adolescent Psychiatry, Psychosomatics and Psychotherapy, Ludwig-Maximilians-Universität München, Waltherstr. 23, 80337, Munich, Germany.
Psychiatry Neuroimaging Laboratory, Brigham and Women's Hospital, Harvard Medical School, Boston, MA, USA.
Brain Imaging Behav. 2021 Apr;15(2):576-584. doi: 10.1007/s11682-020-00370-y.
Sport-related brain injury is very common, and the potential long-term effects include a wide range of neurological and psychiatric symptoms, and potentially neurodegeneration. Around the globe, researchers are conducting neuroimaging studies on primarily homogenous samples of athletes. However, neuroimaging studies are expensive and time consuming, and thus current findings from studies of sport-related brain injury are often limited by small sample sizes. Further, current studies apply a variety of neuroimaging techniques and analysis tools which limit comparability among studies. The ENIGMA Sports Injury working group aims to provide a platform for data sharing and collaborative data analysis thereby leveraging existing data and expertise. By harmonizing data from a large number of studies from around the globe, we will work towards reproducibility of previously published findings and towards addressing important research questions with regard to diagnosis, prognosis, and efficacy of treatment for sport-related brain injury. Moreover, the ENIGMA Sports Injury working group is committed to providing recommendations for future prospective data acquisition to enhance data quality and scientific rigor.
运动相关性脑损伤非常常见，其潜在的长期影响包括广泛的神经和精神症状，以及潜在的神经退行性变。在全球范围内，研究人员正在对主要同质的运动员样本进行神经影像学研究。然而，神经影像学研究既昂贵又耗时，因此，目前有关运动相关性脑损伤的研究结果往往受到样本量小的限制。此外，目前的研究应用了各种神经影像学技术和分析工具，限制了研究之间的可比性。ENIGMA 运动损伤工作组旨在提供一个数据共享和协作数据分析的平台，从而利用现有数据和专业知识。通过协调来自全球大量研究的数据，我们将努力重现先前发表的研究结果，并解决与运动相关性脑损伤的诊断、预后和治疗效果相关的重要研究问题。此外，ENIGMA 运动损伤工作组致力于为未来前瞻性数据采集提供建议，以提高数据质量和科学严谨性。
