Department of Psychiatry and Psychotherapy, Charité - Universitätsmedizin Berlin (Campus Charité Mitte), Berlin, Germany.
Max Planck Centre for Computational Psychiatry and Ageing Research & Wellcome Centre for Human Neuroimaging, University College London, London, UK.
Eur Arch Psychiatry Clin Neurosci. 2021 Sep;271(6):1027-1034. doi: 10.1007/s00406-020-01176-1. Epub 2020 Jul 29.
Large scale prospective cohorts have now been established across several countries, and continents, and among the aims include an assessment of the developmental trajectory of mental disorders. This level of international cooperation helps transfer research findings to new social contexts as well as enabling an assessment of which findings can be replicated, and which interventions are most effective, in different social and cultural settings. However, data sharing across different regional and national health care systems requires a careful consideration of different standards in ethical research, data protection and patient care, including respect for patients' rights, in cooperating jurisdictions. In our review, we discuss ethical, legal and practical challenges associated with such cooperation with a focus on research participants, specifically patient recruitment, by considering the instance of China and Germany. Our broader aim is to promote international cooperation by identifying key challenges that arise in international cooperation, and to facilitate an exchange in relation to legal and practical approaches.
现在已经在多个国家和大洲建立了大规模的前瞻性队列研究，其中的目标之一是评估精神障碍的发展轨迹。这种国际合作的水平有助于将研究结果转移到新的社会环境中，并评估哪些发现可以在不同的社会和文化环境中得到复制，以及哪些干预措施最为有效。然而，在不同的地区和国家医疗保健系统之间共享数据需要仔细考虑伦理研究、数据保护和患者护理方面的不同标准，包括在合作司法管辖区尊重患者权利。在我们的综述中，我们讨论了与这种合作相关的伦理、法律和实际挑战，重点是研究参与者，特别是考虑到中国和德国的情况，患者招募。我们的更广泛目标是通过确定国际合作中出现的关键挑战来促进国际合作，并促进关于法律和实际方法的交流。
