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基于年龄结构模型的 COVID-19 大流行数据驱动研究,以及在不同干预策略下巴西医疗体系崩溃的预测。

Data-driven study of the COVID-19 pandemic via age-structured modelling and prediction of the health system failure in Brazil amid diverse intervention strategies.

机构信息

International Institute of Physics, Federal University of Rio Grande do Norte, Natal, RN, Brazil.

Grupo de Física da Matéria Condensada, Núcleo de Ciências Exatas-NCEx, Campus Arapiraca, Universidade Federal de Alagoas, Arapiraca, AL, Brazil.

出版信息

PLoS One. 2020 Jul 30;15(7):e0236310. doi: 10.1371/journal.pone.0236310. eCollection 2020.

Abstract

In this work we propose a data-driven age-structured census-based SIRD-like epidemiological model capable of forecasting the spread of COVID-19 in Brazil. We model the current scenario of closed schools and universities, social distancing of people above sixty years old and voluntary home quarantine to show that it is still not enough to protect the health system by explicitly computing the demand for hospital intensive care units. We also show that an urgent intense quarantine might be the only solution to avoid the collapse of the health system and, consequently, to minimize the quantity of deaths. On the other hand, we demonstrate that the relaxation of the already imposed control measures in the next days would be catastrophic.

摘要

在这项工作中,我们提出了一个基于数据的、具有年龄结构的、基于人口普查的 SIRD 样流行病学模型,能够预测 COVID-19 在巴西的传播。我们对目前关闭学校和大学、60 岁以上人群保持社交距离和自愿居家隔离的情况进行建模,以表明仅通过明确计算对医院重症监护病房的需求,还不足以保护卫生系统。我们还表明,紧急强化隔离可能是避免卫生系统崩溃的唯一解决方案,从而最大限度地减少死亡人数。另一方面,我们证明,在未来几天放宽已经实施的控制措施将是灾难性的。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3bdb/7392258/631cd92187e4/pone.0236310.g001.jpg

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