• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利：CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法，用中文像聊天一样搜索，搜遍4000万医学文献。AI智能推荐，让科研检索更轻松。

立即免费搜索

文件翻译

保留排版，准确专业，支持PDF/Word/PPT等文件格式，支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述，25分钟生成高质量综述，智能提取关键信息，辅助科研写作。

立即免费体验

用高灵敏度石英晶体微天平免疫传感器快速检测粪便样本中的[具体物质未给出] 。

Rapid Detection of in Feces Sample by Highly Sensitive Quartz Crystal Microbalance Immunosensor.

作者信息

Hou Kaijian, Zhao Pingsen, Chen Yongru, Li Guiping, Lin Yu, Chen Danjie, Zhu Dan, Wu Zezhen, Lian Danchun, Huang Xiaojun, Li Jilin

机构信息

Department of Endocrine and Metabolic Diseases, Longhu Hospital, The First Affiliated Hospital of Shantou University Medical College, Shantou, China.

Department of Laboratory Medicine, Yuebei People's Hospital, Shantou University Medical College, Shaoguan, China.

出版信息

Front Chem. 2020 Jul 7;8:548. doi: 10.3389/fchem.2020.00548. eCollection 2020.

DOI:10.3389/fchem.2020.00548
PMID:32733849
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7358898/
Abstract

In this work, a quartz crystal microbalance (QCM) sensor has been fabricated using immunoassay for sensitive determination of . Au nanoparticle has been used for amplifying sandwich assays. The proposed immunosensor exhibited a linear detection range between 10 and 10 CFU/mL with a limit of detection of 2.1 × 10 CFU/mL. The proposed immunosensor exhibited good selectivity for sensing with low cross reactivity for other foodborne pathogens such as , and . In addition, the proposed immunosensor has been successfully used for detection in feces samples and food samples. The frequency decreases of 12, 17, and 10 Hz were observed from the milk samples consisting of the mixtures of , and . The frequency decreases of 8, 15, and 7 Hz were observed from the feces samples consisting of the mixtures of , and .

摘要

在这项工作中，已使用免疫测定法制造了一种石英晶体微天平（QCM）传感器，用于灵敏地测定……已使用金纳米颗粒来放大夹心测定法。所提出的免疫传感器在10至10 CFU/mL之间呈现线性检测范围，检测限为2.1×10 CFU/mL。所提出的免疫传感器对……传感表现出良好的选择性，对其他食源性病原体如……、……和……具有低交叉反应性。此外，所提出的免疫传感器已成功用于粪便样本和食品样本中的……检测。从由……、……和……混合物组成的牛奶样本中观察到频率下降分别为12、17和10 Hz。从由……、……和……混合物组成的粪便样本中观察到频率下降分别为8、15和7 Hz。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/d29b30396300/fchem-08-00548-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/12e5a93dcd36/fchem-08-00548-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/6bdf87917d6f/fchem-08-00548-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/3a2b8b65f530/fchem-08-00548-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/e38f269080dc/fchem-08-00548-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/328b44634c99/fchem-08-00548-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/97bb52f90c84/fchem-08-00548-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/d29b30396300/fchem-08-00548-g0007.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/12e5a93dcd36/fchem-08-00548-g0001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/6bdf87917d6f/fchem-08-00548-g0002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/3a2b8b65f530/fchem-08-00548-g0003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/e38f269080dc/fchem-08-00548-g0004.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/328b44634c99/fchem-08-00548-g0005.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/97bb52f90c84/fchem-08-00548-g0006.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3fce/7358898/d29b30396300/fchem-08-00548-g0007.jpg

相似文献

1
Rapid Detection of in Feces Sample by Highly Sensitive Quartz Crystal Microbalance Immunosensor.用高灵敏度石英晶体微天平免疫传感器快速检测粪便样本中的[具体物质未给出] 。
Front Chem. 2020 Jul 7;8:548. doi: 10.3389/fchem.2020.00548. eCollection 2020.
2
Sensitive detection of Campylobacter jejuni using nanoparticles enhanced QCM sensor.基于纳米粒子增强的 QCM 传感器灵敏检测空肠弯曲菌
Biosens Bioelectron. 2016 Apr 15;78:328-336. doi: 10.1016/j.bios.2015.11.033. Epub 2015 Nov 14.
3
Real-time and sensitive detection of Salmonella Typhimurium using an automated quartz crystal microbalance (QCM) instrument with nanoparticles amplification.利用自动化石英晶体微天平（QCM）仪器和纳米粒子扩增技术实时、灵敏地检测鼠伤寒沙门氏菌。
Talanta. 2013 Oct 15;115:761-7. doi: 10.1016/j.talanta.2013.06.034. Epub 2013 Jun 28.
4
Quartz crystal microbalance-based aptasensor integrated with magnetic pre-concentration system for detection of Listeria monocytogenes in food samples.基于石英晶体微天平的适体传感器与磁预浓缩系统集成，用于检测食品样品中的单核细胞增生李斯特菌。
Mikrochim Acta. 2024 Apr 3;191(5):235. doi: 10.1007/s00604-024-06307-2.
5
A piezoelectric immunosensor for specific capture and enrichment of viable pathogens by quartz crystal microbalance sensor, followed by detection with antibody-functionalized gold nanoparticles.基于石英晶体微天平传感器的压电免疫传感器通过抗体功能化的金纳米粒子进行特异性捕获和富集活病原体，然后进行检测。
Biosens Bioelectron. 2012 Oct-Dec;38(1):177-83. doi: 10.1016/j.bios.2012.05.024. Epub 2012 May 29.
6
Rapid and Sensitive Detection of Campylobacter jejuni in Poultry Products Using a Nanoparticle-Based Piezoelectric Immunosensor Integrated with Magnetic Immunoseparation.基于纳米颗粒的压电免疫传感器与磁性免疫分离集成快速灵敏检测禽产品中的空肠弯曲菌
J Food Prot. 2018 Aug;81(8):1321-1330. doi: 10.4315/0362-028X.JFP-17-381.
7
Label-free capacitive immunosensor based on quartz crystal Au electrode for rapid and sensitive detection of Escherichia coli O157:H7.基于石英晶体金电极的无标记电容免疫传感器用于快速灵敏检测大肠杆菌 O157:H7。
Anal Chim Acta. 2011 Feb 14;687(1):89-96. doi: 10.1016/j.aca.2010.12.018. Epub 2010 Dec 21.
8
A single-walled carbon nanotubes-based electrochemical impedance immunosensor for on-site detection of Listeria monocytogenes.基于单壁碳纳米管的电化学阻抗免疫传感器用于现场检测单核细胞增生李斯特菌。
J Food Sci. 2022 Jan;87(1):280-288. doi: 10.1111/1750-3841.15996. Epub 2021 Dec 21.
9
Rapid and simultaneous quantification of 4 urinary proteins by piezoelectric quartz crystal microbalance immunosensor array.通过压电石英晶体微天平免疫传感器阵列快速同时定量4种尿液蛋白质。
Clin Chem. 2006 Dec;52(12):2273-80. doi: 10.1373/clinchem.2006.073569. Epub 2006 Oct 19.
10
[Rapid detection of diethylstilbestrol using a quartz crystal microbalance with gold nanoparticals amplification].[基于金纳米颗粒放大的石英晶体微天平快速检测己烯雌酚]
Zhonghua Yu Fang Yi Xue Za Zhi. 2016 Mar;50(3):270-3. doi: 10.3760/cma.j.issn.0253-9624.2016.03.016.

引用本文的文献

1
Are Aptamer-Based Biosensors the Future of the Detection of the Human Gut Microbiome?-A Systematic Review and Meta-Analysis.基于适体的生物传感器是否是人类肠道微生物组检测的未来？——系统评价和荟萃分析。
Biosensors (Basel). 2024 Sep 2;14(9):423. doi: 10.3390/bios14090423.
2
Progress and Challenge of Sensors for Dairy Food Safety Monitoring.用于乳制品食品安全监测的传感器的进展与挑战。
Sensors (Basel). 2024 Feb 21;24(5):1383. doi: 10.3390/s24051383.
3
Epidemiological Analysis of Global and Regional Lung Cancer Mortality: Based on 30-Year Data Analysis of Global Burden Disease Database.

本文引用的文献

1
Molecularly imprinted polymer based electrochemical sensor for quantitative detection of SARS-CoV-2 spike protein.基于分子印迹聚合物的电化学传感器用于定量检测新型冠状病毒刺突蛋白
Sens Actuators B Chem. 2022 Feb 15;353:131160. doi: 10.1016/j.snb.2021.131160. Epub 2021 Nov 27.
2
Development of an electrochemical biosensor for phylogenetic analysis of Amaryllidaceae based on the enhanced electrochemical fingerprint recorded from plant tissue.基于植物组织记录的增强电化学指纹图谱的石蒜科系统发育分析电化学生物传感器的研制。
Biosens Bioelectron. 2020 Jul 1;159:112212. doi: 10.1016/j.bios.2020.112212. Epub 2020 Apr 15.
3
全球及区域肺癌死亡率的流行病学分析：基于全球疾病负担数据库30年数据分析
Healthcare (Basel). 2023 Nov 7;11(22):2920. doi: 10.3390/healthcare11222920.
4
Development of Electrochemical Sensor Using Iron (III) Phthalocyanine/Gold Nanoparticle/Graphene Hybrid Film for Highly Selective Determination of Nicotine in Human Salivary Samples.基于铁（III）酞菁/金纳米粒子/石墨烯杂化膜的电化学传感器的研制及其在人唾液样品中尼古丁的高选择性测定
Biosensors (Basel). 2023 Aug 23;13(9):839. doi: 10.3390/bios13090839.
5
Biosensors for point-of-care testing and personalized monitoring of gastrointestinal microbiota.用于即时检测和胃肠道微生物群个性化监测的生物传感器。
Front Microbiol. 2023 May 5;14:1114707. doi: 10.3389/fmicb.2023.1114707. eCollection 2023.
6
Explore and Analyze the Composition and Characteristics of Intestinal Microbiota between Gastric Cancer Patients and Healthy People.探索和分析胃癌患者与健康人肠道微生物群的组成及特征。
Evid Based Complement Alternat Med. 2022 Sep 8;2022:5834293. doi: 10.1155/2022/5834293. eCollection 2022.
7
Bulk and Surface Acoustic Wave Biosensors for Milk Analysis.用于牛奶分析的体声波和表面声波生物传感器。
Biosensors (Basel). 2022 Aug 5;12(8):602. doi: 10.3390/bios12080602.
8
Electrochemical Biosensing Interface Based on Carbon Dots-FeO Nanomaterial for the Determination of O157:H7.基于碳点-氧化亚铁纳米材料的电化学生物传感界面用于检测O157:H7
Front Chem. 2021 Nov 19;9:769648. doi: 10.3389/fchem.2021.769648. eCollection 2021.
9
Preparation of Electrochemical Sensor Based on Zinc Oxide Nanoparticles for Simultaneous Determination of AA, DA, and UA.基于氧化锌纳米颗粒的电化学传感器用于同时测定抗坏血酸、多巴胺和尿酸的制备
Front Chem. 2020 Nov 25;8:592538. doi: 10.3389/fchem.2020.592538. eCollection 2020.
10
Electrochemical Determination of Nicotine in Tobacco Products Based on Biosynthesized Gold Nanoparticles.基于生物合成金纳米粒子的烟草制品中尼古丁的电化学测定
Front Chem. 2020 Oct 20;8:593070. doi: 10.3389/fchem.2020.593070. eCollection 2020.
Effect of aqueous extract on survival of and and on sensorial and functional properties of synbiotic yogurt.
水提取物对合生元酸奶的存活率以及感官和功能特性的影响。
Food Sci Nutr. 2020 Jan 20;8(2):1254-1263. doi: 10.1002/fsn3.1414. eCollection 2020 Feb.
4
Inhibitory effect of Bifidobacterium bifidum ATCC 29521 on colitis and its mechanism.双歧杆菌 ATCC 29521 对结肠炎的抑制作用及其机制。
J Nutr Biochem. 2020 May;79:108353. doi: 10.1016/j.jnutbio.2020.108353. Epub 2020 Feb 5.
5
Formation and stabilization of colloidal ultra-small palladium nanoparticles on diamine-modified Cr-MIL-101: Synergic boost to hydrogen production from formic acid.二胺功能化 Cr-MIL-101 上胶体超小钯纳米粒子的形成和稳定：协同促进甲酸产氢。
J Colloid Interface Sci. 2020 May 1;567:126-135. doi: 10.1016/j.jcis.2020.01.087. Epub 2020 Feb 1.
6
Infrageneric phylogenetics investigation of Chimonanthus based on electroactive compound profiles.基于电活性化合物特征的蜡梅属种下系统发育研究。
Bioelectrochemistry. 2020 Jun;133:107455. doi: 10.1016/j.bioelechem.2020.107455. Epub 2020 Jan 15.
7
Detection of DDT and carbaryl pesticides in honey by means of immunosensors based on high fundamental frequency quartz crystal microbalance (HFF-QCM).基于高基频石英晶体微天平（HFF-QCM）的免疫传感器检测蜂蜜中的滴滴涕和carbaryl 农药。
J Sci Food Agric. 2020 Apr;100(6):2468-2472. doi: 10.1002/jsfa.10267. Epub 2020 Feb 7.
8
Electrochemical Sensors, a Bright Future in the Fabrication of Portable Kits in Analytical Systems.电化学传感器：分析系统中便携式试剂盒制造的光明未来。
Chem Rec. 2020 Jul;20(7):682-692. doi: 10.1002/tcr.201900092. Epub 2019 Dec 17.
9
Corrigendum: Cell-Free Spent Media Obtained From and Grown in Media Supplemented with 3'-Sialyllactose Modulate Virulence Gene Expression in O157:H7 and Typhimurium.勘误：从在添加3'-唾液酸乳糖的培养基中培养的[具体菌种1]和[具体菌种2]获得的无细胞用过培养基调节O157:H7大肠杆菌和鼠伤寒沙门氏菌的毒力基因表达。
Front Microbiol. 2019 Nov 14;10:2490. doi: 10.3389/fmicb.2019.02490. eCollection 2019.
10
Advanced Evanescent-Wave Optical Biosensors for the Detection of Nucleic Acids: An Analytic Perspective.用于核酸检测的先进倏逝波光学生物传感器：分析视角
Front Chem. 2019 Oct 25;7:724. doi: 10.3389/fchem.2019.00724. eCollection 2019.