Ophthalmology Department, Beijing Tongren Hospital, Beijing, China.
Neurology Department, Beijing Tongren Hospital, Beijing, China.
Ocul Immunol Inflamm. 2021 Jul 4;29(5):922-925. doi: 10.1080/09273948.2019.1704027. Epub 2020 Jul 31.
: The objective of this study was to report a case of bilateral necrotizing retinitis following viral encephalitis caused by the pseudorabies virus.: A 49-year-old male had decreased bilateral visual acuity after the recovery of consciousness for one month. He had been in an unconsciousness status due to encephalitis for two months before the ocular symptoms developed. He was a pig slaughterer. Ocular ultrasound showed bilateral vitreous haze and retinal detachment. A vitrectomy and silicone oil tamponade were performed on the left eye. During surgery, massive periphery retinal necrosis appearing as a tattered fish net, and multiple retinal holes were observed. The pseudorabies virus was detected by next-generation sequencing in the vitreous specimen.: The pseudorabies virus may cause bilateral necrotizing retinitis following viral encephalitis among those with close contact to pigs. Intraocular fluid provides a greater selection of samples and a longer time window for pathogenic detection.
: 本研究旨在报告一例由伪狂犬病病毒引起的病毒性脑炎后双侧坏死性视网膜炎病例。: 一名 49 岁男性，在意识恢复一个月后出现双侧视力下降。在眼部症状出现前两个月，他因脑炎处于昏迷状态。他是一名杀猪工。眼部超声显示双眼玻璃体积血和视网膜脱离。左眼行玻璃体切割术联合硅油填充。术中见大量周边网膜坏死，呈破烂渔网样，合并多个视网膜裂孔。玻璃体标本经下一代测序检测到伪狂犬病病毒。: 与猪密切接触者可能会因伪狂犬病病毒引起病毒性脑炎后双侧坏死性视网膜炎。眼内液为病原体检测提供了更大的样本选择和更长的时间窗口。
