Charleston Health Equity and Rural Outreach Innovation Center (HEROIC), Ralph H. Johnson VA Medical Center, Charleston, SC
Department of Public Health Sciences, Medical University of South Carolina, Charleston, SC.
Diabetes Care. 2020 Oct;43(10):2460-2468. doi: 10.2337/dc20-0514. Epub 2020 Aug 7.
Geographic and racial/ethnic disparities related to diabetes control and treatment have not previously been examined at the national level.
A retrospective cohort study was conducted in a national cohort of 1,140,634 veterans with diabetes, defined as two or more diabetes ICD-9 codes (250.xx) across inpatient and outpatient records. Main exposures of interest included 125 Veterans Administration Medical Center (VAMC) catchment areas as well as racial/ethnic group. The main outcome measure was HbA level dichotomized at ≥8.0% (≥64 mmol/mol).
After adjustment for age, sex, racial/ethnic group, service-connected disability, marital status, and the van Walraven Elixhauser comorbidity score, the prevalence of uncontrolled diabetes varied by VAMC catchment area, with values ranging from 19.1% to 29.2%. Moreover, these differences largely persisted after further adjusting for medication use and adherence as well as utilization and access metrics. Racial/ethnic differences in diabetes control were also noted. In our final models, compared with non-Hispanic Whites, non-Hispanic Blacks (odds ratio 1.11 [95% credible interval 1.09-1.14]) and Hispanics (1.36 [1.09-1.14]) had a higher odds of uncontrolled HBA level.
In a national cohort of veterans with diabetes, we found geographic as well as racial/ethnic differences in diabetes control rates that were not explained by adjustment for demographics, comorbidity burden, use or type of diabetes medication, health care utilization, access metrics, or medication adherence. Moreover, disparities in suboptimal control appeared consistent across most, but not all, VAMC catchment areas, with non-Hispanic Black and Hispanic veterans having a higher odds of suboptimal diabetes control than non-Hispanic White veterans.
之前尚未在国家层面上检查过与糖尿病控制和治疗相关的地理和种族/民族差异。
对全国范围内患有糖尿病的 1140634 名退伍军人进行了回顾性队列研究,定义为住院和门诊记录中出现两个或多个糖尿病 ICD-9 代码(250.xx)。主要感兴趣的暴露因素包括 125 个退伍军人管理局医疗中心(VAMC)集水区以及种族/民族群体。主要结果测量是将 HbA 水平分为≥8.0%(≥64mmol/mol)。
在调整年龄、性别、种族/民族、与服务相关的残疾、婚姻状况以及 van Walraven Elixhauser 合并症评分后,VAMC 集水区的糖尿病控制率存在差异,范围从 19.1%到 29.2%。此外,在进一步调整药物使用和依从性以及利用和获得指标后,这些差异仍然存在。还注意到了糖尿病控制方面的种族/民族差异。在我们的最终模型中,与非西班牙裔白人相比,非西班牙裔黑人(比值比 1.11[95%可信区间 1.09-1.14])和西班牙裔(1.36[1.09-1.14])的 HbA 水平控制不佳的可能性更高。
在患有糖尿病的全国性退伍军人队列中,我们发现糖尿病控制率存在地理和种族/民族差异,这些差异不能通过调整人口统计学、合并症负担、使用或类型的糖尿病药物、医疗保健利用、获取指标或药物依从性来解释。此外,在大多数(但不是全部)VAMC 集水区,亚最佳控制的差异似乎一致,而非西班牙裔黑人或西班牙裔退伍军人的亚最佳糖尿病控制可能性高于非西班牙裔白人退伍军人。