Khurana Sumeeta, Sharma Megha
Department of Medical Parasitology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Trop Parasitol. 2020 Jan-Jun;10(1):12-17. doi: 10.4103/tp.TP_84_19. Epub 2020 May 20.
Parasitic keratitis (PK) is unique entity among parasitic infections where corneal involvement could result from direct inoculation of the parasite via exogenous environment or spread via endogenous neighboring organs or as a result of immune-mediated damage secondary to a systemic parasitic infection. Most cases of PK are caused by spp. and Microsporidia spp. though few other parasitic agents can also lead to corneal involvement. Mimicking as other infectious and non-infectious causes of keratitis, PK often escapes detection. This review summarizes the predominant causes of PK along with the epidemiological, clinical and microbiological details of each. Though several gaps exist in our understanding of the prevalence of PK, the one thing for sure is that PK is on the rise. With advanced diagnostic modalities and enough literature on optimal management of cases of PK, it is now imperative that a strong clinical suspicion of PK is kept when examining a case of corneal pathology and adequate investigations are ordered.
寄生性角膜炎（PK）在寄生虫感染中是一种独特的疾病，角膜受累可能是由于寄生虫通过外部环境直接接种、通过邻近的内源性器官传播，或者是由于全身性寄生虫感染继发的免疫介导损伤所致。虽然其他一些寄生虫也可导致角膜受累，但大多数PK病例是由 属和微孢子虫属引起的。PK常被误诊为其他感染性和非感染性角膜炎病因，因而常难以被发现。本综述总结了PK的主要病因以及每种病因的流行病学、临床和微生物学细节。尽管我们对PK的患病率的认识存在一些差距，但有一点可以肯定的是，PK的发病率正在上升。随着先进的诊断方法以及关于PK病例最佳治疗的大量文献的出现，现在在检查角膜病变病例时，必须强烈怀疑PK，并进行充分的检查。
