School of Medicine, University of California, San Francisco, San Francisco, California, USA.
San Francisco Veterans Affairs Health Care System, San Francisco, California, USA.
J Am Geriatr Soc. 2020 Nov;68(11):2638-2642. doi: 10.1111/jgs.16754. Epub 2020 Aug 11.
To determine whether depression and anxiety are associated with advance care planning (ACP) engagement or values concerning future medical care.
Cross-sectional.
English- and Spanish-speaking patients, aged 55 years and older, from a San Francisco, CA, county hospital.
Depression was measured by the Patient Health Questionnaire 8-item scale, and anxiety was measured by the Generalized Anxiety Disorder 7-item scale, using standardized cutoffs of 10 or more for moderate-to-severe symptoms. ACP engagement was measured using validated surveys of ACP behavior change (e.g., self-efficacy and readiness; mean five-point Likert score) and ACP actions (e.g., ask, discuss, and document wishes; 0- to 25-point scale), with higher scores representing higher engagement. In addition, we asked a question about valuing life extension ("some health situations would make life not worth living"). We used adjusted linear and logistic regression.
Mean age of 986 participants was 63 years, 81% were non-White, 39% had limited health literacy, 45% were Spanish speaking, 13% had depression, and 10% had anxiety. After adjustment for demographic and health status variables, participants who were depressed versus not depressed had higher ACP behavior change scores (0.2 points; 95% confidence interval (CI) = 0.06-0.38; P = .007), higher ACP action scores (1.5 points; 95% CI = 0.51-2.57; P = .003), and higher odds of not valuing life extension (odds ratio (OR) = 2.5; 95% CI = 1.5-4.3; P < .001). Results were similar in participants with versus without anxiety (ACP behavior change: 0.2 points; 95% CI = 0.05-0.40; P = .01; ACP action scores: 1.2 points; 95% CI = 0.14-2.32; P = .028; odds of not valuing life extension: OR = 2.3; 95% CI = 1.3-3.9; P = .004).
Depression and anxiety were associated with greater ACP engagement and not valuing life extension. Although the direction of association between ACP engagement and values with anxiety and depression cannot be determined in this cross-sectional study, these conditions may influence ACP preferences. Future studies should assess whether changes in anxiety or depression affect ACP preferences over time.
确定抑郁和焦虑是否与预先医疗护理计划(ACP)的参与或对未来医疗护理的价值观有关。
横断面研究。
来自加利福尼亚州旧金山县医院的 55 岁及以上的讲英语和西班牙语的患者。
使用经过验证的 ACP 行为改变量表(例如自我效能感和准备程度;平均五点李克特评分)和 ACP 行为量表(例如询问、讨论和记录意愿;0-25 分制)来测量抑郁,使用经过验证的广泛性焦虑症 7 项量表来测量焦虑,采用 10 分或更高的标准来衡量中度至重度症状。较高的分数表示更高的参与度。此外,我们询问了一个关于重视生命延长的问题(“某些健康状况会使生活不值得活下去”)。我们使用了调整后的线性和逻辑回归。
986 名参与者的平均年龄为 63 岁,81%为非白人,39%有有限的健康素养,45%讲西班牙语,13%有抑郁,10%有焦虑。在调整了人口统计学和健康状况变量后,与没有抑郁的参与者相比,抑郁的参与者的 ACP 行为改变评分更高(0.2 分;95%置信区间(CI)=0.06-0.38;P=0.007),ACP 行为评分更高(1.5 分;95%CI=0.51-2.57;P=0.003),并且不太重视延长生命的可能性更高(比值比(OR)=2.5;95%CI=1.5-4.3;P<0.001)。在有焦虑和没有焦虑的参与者中,结果相似(ACP 行为改变:0.2 分;95%CI=0.05-0.40;P=0.01;ACP 行为评分:1.2 分;95%CI=0.14-2.32;P=0.028;不重视延长生命的可能性:OR=2.3;95%CI=1.3-3.9;P=0.004)。
抑郁和焦虑与 ACP 参与度的增加和不重视延长生命有关。尽管在这项横断面研究中,无法确定焦虑和抑郁与 ACP 参与度和价值观之间的关联方向,但这些情况可能会影响 ACP 的偏好。未来的研究应该评估焦虑或抑郁的变化是否会随着时间的推移影响 ACP 的偏好。