Hiemori-Kondo Miki
Department of Food Nutrition, Tokushima Bunri University, 180 Nishihama, Yamashiro, Tokushima 770-8514, Japan.
J Clin Biochem Nutr. 2020 Jul;67(1):10-18. doi: 10.3164/jcbn.20-58. Epub 2020 Jun 11.
() is a plant of the Asteraceae family. Its roots and stems have been used for the treatment or the prophylaxis of migraine and tension headache as a traditional Chinese medicine in Japan and Korea. Sesquiterpenoids, lignans, and flavonoids are components of . Regarding the biological activity of , its anti-allergic effect has been researched extensively using IgE antigen-stimulated degranulation of RBL-2H3 cells or passive cutaneous anaphylaxis reaction in experimental animal models. The study of the antioxidant activity of was initiated approximately 15 years ago using assays. In addition, its effect has also been examined in animal models with induced oxidative injury. Moreover, recently, many types of antioxidant compounds have been rapidly and simultaneously identified using the liquid chromatography-mass spectrometry technique. The number of reports on the other functions of this plant, such as its neuroprotective and anti-inflammatory effects, has been increasing. In this review, I summarized the studies of functional foods derived from , which may provide a basis for the development of potential functional foods. Finally, I discuss the future research avenues in this field.
（）是菊科植物。在日本和韩国，其根和茎作为传统中药用于治疗或预防偏头痛和紧张性头痛。倍半萜类、木脂素类和黄酮类是（）的成分。关于（）的生物活性，已在实验动物模型中使用IgE抗原刺激的RBL - 2H3细胞脱颗粒或被动皮肤过敏反应对其抗过敏作用进行了广泛研究。大约15年前开始使用（）测定法对（）的抗氧化活性进行研究。此外，还在诱导氧化损伤的动物模型中检查了其（）作用。而且，最近，使用液相色谱 - 质谱技术已快速且同时鉴定出多种抗氧化化合物。关于这种植物其他功能的报道数量，如神经保护和抗炎作用，一直在增加。在这篇综述中，我总结了源自（）的功能性食品的研究，这可能为潜在功能性食品的开发提供依据。最后，我讨论了该领域未来的研究方向。
