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植物:富含重要营养药物的属——综述

Plants: A Genus Rich in Vital Nutra-pharmaceuticals-A Review.

作者信息

Salehi Bahare, Sener Bilge, Kilic Mehtap, Sharifi-Rad Javad, Naz Rabia, Yousaf Zubaida, Mudau Fhatuwani Nixwell, Fokou Patrick Valere Tsouh, Ezzat Shahira M, El Bishbishy Mahitab H, Taheri Yasaman, Lucariello Giuseppe, Durazzo Alessandra, Lucarini Massimo, Suleria Hafiz Ansar Rasul, Santini Antonello

机构信息

Student Research Committee, School of Medicine, Bam University of Medical Sciences, Bam, Iran.

Department of Pharmacognosy, Faculty of Pharmacy, Gazi University, 06330 Ankara, Turkey.

出版信息

Iran J Pharm Res. 2019 Fall;18(Suppl1):68-89. doi: 10.22037/ijpr.2019.112501.13795.

Abstract

species, known as "Yams," belong to family . This genus consists of more than 600 species distributed from Africa, Asia, the Caribbean's South America, and the South Pacific islands. Their organoleptic properties make them the most widely used carbohydrate food and dietary supplements. The underground and/or aerial tubers represent valuable sources of proteins, fats, and vitamins for millions of people in West Africa. This review gives a shot of secondary metabolites of plants, including steroids, clerodane diterpenes, quinones, cyanidins, phenolics, diarylheptanoids, and nitrogen-containing compounds. This review collected the evidence on biological properties of description , including and studies. species contain promising bioactive molecules diosgenin that support their different biological properties, including antioxidant, hypoglycaemic, hypolipidemic, anti- antimicrobial, inflammatory, antiproliferative, androgenic, estrogenic, and contraceptive drugs. Indeed, besides its nutrient values, is a potential source of bioactive substances of interest in the prevention/treatment of several diseases, and thus represents a great challenge in developing countries. However, ethnomedicinal potential should be validated and further researches on pharmacological properties and phytochemical composition should be carried out. Particularly, doing some studies to convert the preclinical results to clinical efficacy should be guaranteed. Dioscorea, Food plant, Traditional use, Phytochemistry, Pharmacological activities.

摘要

薯蓣属植物,被称为“山药”,隶属于薯蓣科。该属包含600多个物种,分布于非洲、亚洲、加勒比地区、南美洲以及南太平洋诸岛。其感官特性使其成为使用最为广泛的碳水化合物类食物及膳食补充剂。地下块茎和/或地上块茎是西非数百万人蛋白质、脂肪和维生素的重要来源。本综述介绍了薯蓣属植物的次生代谢产物,包括甾体类、克罗烷二萜类、醌类、花青素、酚类、二芳基庚烷类和含氮化合物。本综述收集了关于其生物学特性的证据,包括体外和体内研究。薯蓣属植物含有如薯蓣皂苷元等具有潜在生物活性的分子,这些分子支持其不同的生物学特性,包括抗氧化、降血糖、降血脂、抗菌、抗炎、抗增殖、雄激素样、雌激素样以及避孕等作用。事实上,除了其营养价值外,薯蓣属植物还是预防/治疗多种疾病的潜在生物活性物质来源,因此在发展中国家是一个巨大的挑战。然而,民族药用潜力应得到验证,并且应进一步开展关于其药理特性和植物化学成分的研究。特别要保证进行一些将临床前结果转化为临床疗效的研究。薯蓣属、食用植物、传统用途、植物化学、药理活性

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/22dd/7393038/e0a20cf7a4ce/ijpr-18-068-g001.jpg

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