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拨开杂草:大麻使用频率测量与延迟折扣之间的关系。

Sifting through the weeds: Relationships between cannabis use frequency measures and delay discounting.

作者信息

Sofis Michael J, Borodovsky Jacob T, Pike Chelsea K, Liu Lili, Jacobson Nicholas C, Budney Alan J

机构信息

Geisel School of Medicine, Dartmouth College, Center for Technology and Behavioral Health, 46 Centerra Parkway, Suite 315, Lebanon, NH, USA.

Department of Psychiatry, Washington University School of Medicine in St. Louis, 660 South Euclid Avenue, Box 8134, St. Louis, MO 63110, USA.

出版信息

Addict Behav. 2021 Jan;112:106573. doi: 10.1016/j.addbeh.2020.106573. Epub 2020 Jul 24.

Abstract

BACKGROUND

Delay Discounting (DD) relates to more frequent cannabis use, but results are variable, potentially because of variations in whether integrated or single-item measures are used, and whether the timeframe of measures is narrow or broad. Explicating the relationship between DD and cannabis use may result from comparing use indices that vary on these characteristics.

METHODS

This online study of current cannabis users (n = 1,800) assessed DD and three cannabis use frequency items: number of days of use in the past month, times used per day, and weekly-monthly use. A fourth index derived with Latent Class Analysis (LCA) integrated days per month and times per day to try to better characterize frequency patterns. Effect sizes reflecting relations between cannabis use frequency indices and DD were compared.

RESULTS

Three frequency classes emerged from the LCA (Low-Moderate-High). DD was significantly associated with times per day (r = 0.11, d = 0.21), days of use (r = 0.09, d = 0.18), and the LCA index (r = 0.06, d = 0.13), but not weekly-monthly use (r = 0.04, d = 0.09). Times per day was more strongly related to DD than LCA classes (p < 0.01) and weekly-monthly use (p < 0.05), but not days of use (p = 0.66). Days of use exhibited a stronger relationship with DD than weekly-monthly use (p < 0.001), but not LCA classes (p = 0.06).

CONCLUSIONS

Cannabis use frequency measures with narrower timeframes may demonstrate stronger positive relationships to DD. The LCA index did not improve the relationship between frequency and DD, potentially because of shared variance between use days and times per day. Specific characteristics of cannabis use frequency may be particularly indicative of excessive DD.

摘要

背景

延迟折扣(DD)与更频繁的大麻使用有关,但结果存在差异,这可能是由于使用的是综合测量还是单项测量,以及测量的时间范围是窄还是宽存在差异。通过比较在这些特征上有所不同的使用指标,可能有助于阐明DD与大麻使用之间的关系。

方法

这项针对当前大麻使用者(n = 1800)的在线研究评估了DD和三项大麻使用频率指标:过去一个月的使用天数、每天使用次数以及每周至每月的使用情况。通过潜在类别分析(LCA)得出的第四个指标整合了每月使用天数和每天使用次数,以试图更好地描述频率模式。比较了反映大麻使用频率指标与DD之间关系的效应大小。

结果

LCA得出了三个频率类别(低 - 中 - 高)。DD与每天使用次数(r = 0.11,d = 0.21)、使用天数(r = 0.09,d = 0.18)以及LCA指标(r = 0.06,d = 0.13)显著相关,但与每周至每月的使用情况(r = 0.04,d = 0.09)无关。每天使用次数与DD的相关性比LCA类别(p < 0.01)和每周至每月的使用情况(p < 0.05)更强,但与使用天数无关(p = 0.66)。使用天数与DD的关系比每周至每月的使用情况更强(p < 0.001),但与LCA类别无关(p = 0.06)。

结论

时间范围较窄的大麻使用频率测量指标可能与DD呈现出更强的正相关关系。LCA指标并未改善频率与DD之间的关系,这可能是由于使用天数和每天使用次数之间存在共同方差。大麻使用频率的特定特征可能特别表明存在过度的DD。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/d6c1/7572823/71be020ef3b5/nihms-1615301-f0001.jpg

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