Specialist Doctor of Infectious Disease and Clinical Microbology, Department of Infectious Diseases and Clinical Microbiology, Sakarya University Training and Research Hospital, Sakarya, Turkey.
Professor Doctor of Infectious Disease and Clinical Microbology, Department of Infectious Diseases and Clinical Microbiology, Sakarya University Training and Research Hospital, Sakarya, Turkey.
Scott Med J. 2020 Nov;65(4):127-132. doi: 10.1177/0036933020949253. Epub 2020 Aug 17.
The first case of a novel coronavirus (COVID-19) infection was detected in Wuhan, fever and respiratory symptoms have been frequently reported in patients infected with this virus.
It was aimed to compare the symptoms of patients with COVID-19 positivity and patients without COVID-19 positivity hospitalized with suspicion of COVID-19.
Patients presenting to the Sakarya University Training and Research Hospital with suspicion of COVID-19 were included in the study. Samples were obtained from the patients and PCR tests were performed; the patients were grouped as COVID-19 positive and COVID-19 negative; these two groups were questioned for 15 symptoms and the results were compared.
A total of 297 patients with suspicion of COVID-19 were included in the study. COVID-19 was positive in 143 patients and negative in 154 patients. The most common symptoms in the COVID-19 positive group were: cough (56.6%), weakness (56.6%), taste disorder (35.7%), myalgia (34.3%), and fever (33.6%); and in the COVID-19 negative group: cough (63%), weakness (45.5%), dyspnea (29.9%), headache (27.3%) and fever (24.7%). When these two groups were compared, taste disorder, smell disorder and diarrhea were significantly higher in the COVID-19 positive group (p = <0,00001, p = 0,00001 and p = 0,02).
Our study showed that taste and smell disorders and diarrhea were important markers in COVID-19 infection.
首例新型冠状病毒(COVID-19)感染病例在武汉被检测到,感染该病毒的患者常出现发热和呼吸道症状。
旨在比较 COVID-19 阳性患者和因 COVID-19 疑似住院的 COVID-19 阴性患者的症状。
将怀疑患有 COVID-19 的患者纳入本研究。从患者身上采集样本并进行 PCR 检测;将患者分为 COVID-19 阳性和 COVID-19 阴性组;询问这两组患者 15 种症状,并比较结果。
本研究共纳入 297 例疑似 COVID-19 患者。COVID-19 阳性患者 143 例,阴性患者 154 例。COVID-19 阳性组最常见的症状为:咳嗽(56.6%)、乏力(56.6%)、味觉障碍(35.7%)、肌痛(34.3%)和发热(33.6%);而 COVID-19 阴性组最常见的症状为:咳嗽(63%)、乏力(45.5%)、呼吸困难(29.9%)、头痛(27.3%)和发热(24.7%)。两组比较,COVID-19 阳性组味觉障碍、嗅觉障碍和腹泻的发生率显著更高(p<0.00001,p=0.00001 和 p=0.02)。
本研究表明味觉和嗅觉障碍及腹泻是 COVID-19 感染的重要标志物。