疫苗犹豫的同行评议期刊全球科学文献计量分析（1990-2019 年）。

BACKGROUND: Vaccine hesitancy is a growing threat to national and global health security. The current study was undertaken to provide insights into the global scientific literature on vaccine hesitancy in peer-reviewed journals. METHOD: The current study was a descriptive bibliometric study. A validated search strategy on vaccine hesitancy was implemented using SciVerse Scopus. Bibliometric indicators such as (1) annual growth of publications, (2) key players, (3) research themes, (4) pathogens/diseases encountered, (5) top-cited documents, and (6) annual growth of publications stratified by world region and by age category were presented. The study period was from 1990 to 2019. RESULTS: Search strategy found 2791 documents. The h-index of the retrieved literature was 89. The leading journal was Vaccine (369; 13.2%%) followed by Human Vaccines and Immunotherapeutics (129; 4.6%). Authors from the USA led with 1125 (40.3%) followed by authors from Italy (234; 8.4%) and the UK (204; 7.3%). The US CDC led with 140 (5.0%) documents followed by Emory University (USA) (81, 2.9%). The list of active authors included six from the USA while the remaining were from France, Australia, and Canada. Research themes in the retrieved literature focused on influenza, human papillomavirus, and the role of parents in immunization of their children. The region of the Americas and the European region had the greatest share of publications and showed steep growth of publications lately. Vaccine hesitancy research on adolescents was most noticed after 2007 while that on children was present all the time but escalated lately. Titles/abstracts analysis indicated that 621(22.3%) documents focused on influenza, 392 (14.0%) focused on Human papillomavirus, and 292 (10.5%) focused on measles. The top-cited documents in literature published after 2015 focused on the definition and strategies to overcome vaccine hesitancy. CONCLUSION: The last decade witnessed a noticeable increase in the number of publications. Influenza vaccine and parental concerns about the human papillomavirus vaccine were the main focus of the retrieved literature. Information on vaccine hesitancy needs to be collected from all countries to build a better coalition against the anti-vaccination groups. Re-building trust in vaccines requires targeting parents by providing adequate information on the vaccines.

背景：疫苗犹豫是对国家和全球健康安全的日益严重的威胁。本研究旨在提供有关同行评审期刊中疫苗犹豫的全球科学文献的见解。

方法：本研究是一项描述性的文献计量研究。使用 SciVerse Scopus 实施了一项经过验证的疫苗犹豫搜索策略。呈现了以下指标：（1）出版物的年增长率，（2）主要参与者，（3）研究主题，（4）遇到的病原体/疾病，（5）被引频次最高的文献，以及（6）按世界区域和年龄类别分层的出版物年增长率。研究时间为 1990 年至 2019 年。

结果：搜索策略发现了 2791 篇文献。检索文献的 h 指数为 89。领先的期刊是《疫苗》（369 篇；13.2%），其次是《人类疫苗与免疫疗法》（129 篇；4.6%）。来自美国的作者以 1125 篇（40.3%）领先，其次是意大利（234 篇；8.4%）和英国（204 篇；7.3%）。美国疾病预防控制中心以 140 篇（5.0%）的文献位居榜首，其次是美国埃默里大学（81 篇，2.9%）。活跃作者名单包括 6 名来自美国，其余来自法国、澳大利亚和加拿大。检索文献中的研究主题侧重于流感、人乳头瘤病毒以及父母在儿童免疫接种中的作用。美洲和欧洲地区的出版物份额最大，最近出版物的增长率也很高。对青少年的疫苗犹豫研究在 2007 年后最为引人注目，而对儿童的研究则一直存在，但最近有所增加。标题/摘要分析表明，621 篇（22.3%）文献侧重于流感，392 篇（14.0%）文献侧重于人乳头瘤病毒，292 篇（10.5%）文献侧重于麻疹。2015 年后发表的文献中被引频次最高的文献侧重于疫苗犹豫的定义和克服策略。

结论：过去十年，出版物数量明显增加。流感疫苗和父母对人乳头瘤病毒疫苗的担忧是检索文献的主要焦点。需要从所有国家收集有关疫苗犹豫的信息，以建立一个更好的联盟来对抗反疫苗团体。重新建立对疫苗的信任需要通过提供有关疫苗的充分信息来针对父母。