Nell Hodgson Woodruff School of Nursing, Emory University, Atlanta, Georgia, USA.
Department of Surgery, Division of Transplantation, Emory University School of Medicine, Atlanta, Georgia, USA.
Am J Transplant. 2021 Jan;21(1):314-321. doi: 10.1111/ajt.16277. Epub 2020 Sep 15.
Kidney transplant program performance in the United States is commonly measured by posttransplant outcomes. Inclusion of pretransplant measures could provide a more comprehensive assessment of transplant program performance and necessary information for patient decision-making. In this study, we propose a new metric, the waitlisting rate, defined as the ratio of patients who are waitlisted in a center relative to the person-years referred for evaluation to a program. Furthermore, we standardize the waitlisting rate relative to the state average in Georgia, North Carolina, and South Carolina. The new metric was used as a proof-of-concept to assess transplant-program access compared to the existing transplant rate metric. The study cohorts were defined by linking 2017 United States Renal Data System (USRDS) data with transplant-program referral data from the Southeastern United States between January 1, 2012 and December 31, 2016. Waitlisting rate varied across the 9 Southeastern transplant programs, ranging from 10 to 22 events per 100 patient-years, whereas the program-specific waitlisting rate ratio ranged between 0.76 and 1.33. Program-specific waitlisting rate ratio was uncorrelated with the transplant rate ratio (r = -.15, 95% CI, -0.83 to 0.57). Findings warrant collection of national data on early transplant steps, such as referral, for a more comprehensive assessment of transplant program performance and pretransplant access.
美国的肾脏移植项目表现通常通过移植后的结果来衡量。纳入移植前的指标可以更全面地评估移植项目的表现,并为患者的决策提供必要的信息。在这项研究中,我们提出了一个新的指标,即候补率,定义为中心的候补患者人数与转诊到项目的评估人年数的比例。此外,我们将候补率相对于佐治亚州、北卡罗来纳州和南卡罗来纳州的州平均水平进行了标准化。该新指标被用作概念验证,用于评估与现有移植率指标相比的移植项目准入情况。研究队列是通过将 2017 年美国肾脏数据系统(USRDS)的数据与 2012 年 1 月 1 日至 2016 年 12 月 31 日期间美国东南部的移植项目转诊数据相链接来定义的。候补率在 9 个东南移植项目中存在差异,范围为每 100 患者-年 10 至 22 例,而特定项目的候补率比值范围在 0.76 至 1.33 之间。特定项目的候补率比值与移植率比值不相关(r = -.15,95%CI,-0.83 至 0.57)。研究结果表明,有必要收集关于早期移植步骤(如转诊)的全国数据,以更全面地评估移植项目的表现和移植前的准入情况。