Department of Biotechnology - DBTEC, Institute of Health Sciences - ICS, Federal University of Bahia - UFBA, Salvador, Bahia, Brazil.
Braz J Microbiol. 2020 Sep;51(3):1109-1115. doi: 10.1007/s42770-020-00331-z. Epub 2020 Aug 27.
COVID-19 has killed more than 500,000 people worldwide and more than 60,000 in Brazil. Since there are no specific drugs or vaccines, the available tools against COVID-19 are preventive, such as the use of personal protective equipment, social distancing, lockdowns, and mass testing. Such measures are hindered in Brazil due to a restrict budget, low educational level of the population, and misleading attitudes from the federal authorities. Predictions for COVID-19 are of pivotal importance to subsidize and mobilize health authorities' efforts in applying the necessary preventive strategies. The Weibull distribution was used to model the forecast prediction of COVID-19, in four scenarios, based on the curve of daily new deaths as a function of time. The date in which the number of daily new deaths will fall below the rate of 3 deaths per million - the average level in which some countries start to relax the stay-at-home measures - was estimated. If the daily new deaths curve was bending today (i.e., about 1250 deaths per day), the predicted date would be on July 5. Forecast predictions allowed the estimation of overall death toll at the end of the outbreak. Our results suggest that each additional day that lasts to bend the daily new deaths curve may correspond to additional 1685 deaths at the end of COVID-19 outbreak in Brazil (R = 0.9890). Predictions of the outbreak can be used to guide Brazilian health authorities in the decision-making to properly fight COVID-19 pandemic.
新冠病毒已导致全球超过 50 万人死亡,巴西超过 6 万人死亡。由于没有特定的药物或疫苗,针对新冠病毒的现有工具是预防措施,例如使用个人防护设备、保持社交距离、封锁和大规模检测。由于预算有限、人口教育水平低以及联邦当局的误导性态度,巴西在采取这些措施方面受到阻碍。对新冠病毒的预测对于资助和调动卫生当局努力实施必要的预防策略至关重要。我们使用威布尔分布对新冠病毒的预测进行建模,共设想了四种情景,基于每日新增死亡人数随时间的变化曲线。我们对每日新增死亡人数将降至 3 人/百万人以下的日期进行了预测,这一数字是一些国家开始放宽居家隔离措施的平均水平。如果每日新增死亡人数曲线今天开始变平(即每天约有 1250 人死亡),则预计日期将是 7 月 5 日。预测结果允许估算疫情结束时的总死亡人数。我们的研究结果表明,每天新增死亡人数曲线变平的时间每增加一天,巴西新冠疫情结束时的死亡人数可能会增加 1685 人(R=0.9890)。疫情预测可用于指导巴西卫生当局做出决策,以正确应对新冠疫情。