UOC of Internal Medicine-Center of Hypertension and Nephrology Unit, Department of Systems Medicine, University of Rome Tor Vergata, 00133 Rome, Italy.
PhD School of Applied Medical, Surgical Sciences, University of Rome Tor Vergata, 00133 Rome, Italy.
Nutrients. 2020 Aug 20;12(9):2519. doi: 10.3390/nu12092519.
Long-chain ω-3 polyunsaturated fatty acids (PUFAs) are fundamental biocomponents of lipids and cell membranes. They are involved in the maintenance of cellular homeostasis and they are able to exert anti-inflammatory and cardioprotective actions. Thanks to their potential beneficial effects on the cardiovascular system, metabolic axis and body composition, we have examined their action in subjects affected by male obesity secondary hypogonadism (MOSH) syndrome. MOSH syndrome is characterized by the presence of obesity associated with the alteration of sexual and metabolic functions. Therefore, this review article aims to analyze scientific literature regarding the possible benefits of ω-3 PUFA administration in subjects affected by MOSH syndrome. We conclude that there are strong evidences supporting ω-3 PUFA administration and/or supplementation for the treatment and management of MOSH patients.
长链 ω-3 多不饱和脂肪酸（PUFA）是脂质和细胞膜的基本生物成分。它们参与细胞内环境的维持，具有抗炎和心脏保护作用。由于它们对心血管系统、代谢轴和身体成分可能有益，我们研究了它们在男性肥胖伴性腺功能减退症（MOSH）综合征患者中的作用。MOSH 综合征的特征是肥胖与性和代谢功能的改变有关。因此，这篇综述文章旨在分析关于 ω-3 PUFA 给药在 MOSH 综合征患者中的可能益处的科学文献。我们得出结论，有强有力的证据支持 ω-3 PUFA 的给药和/或补充治疗和管理 MOSH 患者。
