Two new diterpenoids from MT-12, an endophytic fungus isolated from .

Two new diterpenoids, penicichrysogene A () and penicichrysogene B (), were isolated from the solid substrate fermentation cultures of MT-12, an endophytic fungus isolated from the medicinal plant of . Their structures were elucidated on the basis of extensive spectroscopic and spectrometric data (1D and 2D NMR, UV, IR, and HRESIMS). The absolute configurations of and were assigned on the basis of experimental and calculated electronic circular dichroism spectra. Compound exhibited inhibitory activity on ATP release of thrombin-activated platelets with IC = 42.7 ± 3.5 μM.