Rossi Rodolfo, Socci Valentina, Talevi Dalila, Mensi Sonia, Niolu Cinzia, Pacitti Francesca, Di Marco Antinisca, Rossi Alessandro, Siracusano Alberto, Di Lorenzo Giorgio
Chair of Psychiatry, Department of Systems Medicine, University of Rome Tor Vergata, Rome, Italy.
Department of Biotechnological and Applied Clinical Sciences, University of L'Aquila, L'Aquila, Italy.
Front Psychiatry. 2020 Aug 7;11:790. doi: 10.3389/fpsyt.2020.00790. eCollection 2020.
The psychological impact of the COronaVIrus Disease 2019 (COVID-19) outbreak and lockdown measures on the Italian population are unknown. The current study assesses rates of mental health outcomes in the Italian general population three to 4 weeks into lockdown measures and explores the impact of COVID-19 related potential risk factors.
A web-based survey spread throughout the internet between March 27 and April 6 2020. Eighteen thousand one hundred forty-seven individuals completed the questionnaire, 79.6% women. Selected outcomes were post-traumatic stress symptoms (PTSS), depression, anxiety, insomnia, perceived stress, and adjustment disorder symptoms (ADS). Seemingly unrelated logistic regression analysis was performed to identify COVID-19 related risk factors.
Endorsement rates for PTSS were 6,604 (37%), 3,084 (17.3%) for depression, 3,700 (20.8%) for anxiety, 1,301 (7.3%) for insomnia, 3,895 (21.8%) for high perceived stress and 4,092 (22.9%) for adjustment disorder. Being woman and younger age were associated with all of the selected outcomes. Quarantine was associated with PTSS, anxiety and ADS. Any recent COVID-related stressful life event was associated with all the selected outcomes. Discontinued working activity due to the COVID-19 was associated with all the selected outcomes, except for ADS; working more than usual was associated with PTSS, Perceived stress and ADS. Having a loved one deceased by COVID-19 was associated with PTSS, depression, perceived stress, and insomnia.
We found high rates of negative mental health outcomes in the Italian general population 3 weeks into the COVID-19 lockdown measures and different COVID-19 related risk factors. These findings warrant further monitoring on the Italian population's mental health.
2019年冠状病毒病（COVID-19）疫情及封锁措施对意大利民众的心理影响尚不清楚。本研究评估了封锁措施实施三至四周后意大利普通人群的心理健康状况，并探讨了与COVID-19相关的潜在风险因素的影响。
2020年3月27日至4月6日在互联网上开展了一项基于网络的调查。18147人完成了问卷，其中79.6%为女性。选定的结果指标为创伤后应激症状（PTSS）、抑郁、焦虑、失眠、感知压力和适应障碍症状（ADS）。进行了看似不相关的逻辑回归分析，以确定与COVID-19相关的风险因素。
PTSS的认可率为6604人（37%），抑郁为3084人（17.3%），焦虑为3700人（20.8%），失眠为1301人（7.3%），高感知压力为3895人（21.8%），适应障碍为4092人（22.9%）。女性和较年轻年龄与所有选定的结果指标相关。隔离与PTSS、焦虑和ADS相关。近期任何与COVID相关的应激性生活事件与所有选定的结果指标相关。因COVID-19而停止工作活动与所有选定的结果指标相关，但ADS除外；工作比平时更多与PTSS、感知压力和ADS相关。有亲人死于COVID-19与PTSS、抑郁、感知压力和失眠相关。
我们发现在COVID-19封锁措施实施三周后，意大利普通人群中负面心理健康结果的发生率较高，且存在不同的与COVID-19相关的风险因素。这些发现值得对意大利人群的心理健康进行进一步监测。
