用于先进应用的生物分子纳米级配位聚合物工程
Engineering of Nanoscale Coordination Polymers with Biomolecules for Advanced Applications.
作者信息
Mu Jing, He Liangcan, Huang Peng, Chen Xiaoyuan
机构信息
Guangdong Key Laboratory for Biomedical Measurements and Ultrasound Imaging, Laboratory of Evolutionary Theranostics, School of Biomedical Engineering, Health Science Center, Shenzhen University, Shenzhen 518060.
Key Laboratory of Optoelectronic Devices and Systems of Ministry of Education and Guangdong Province, College of Optoelectronic Engineering, Shenzhen University, Shenzhen 518060, China.
出版信息
Coord Chem Rev. 2019 Nov 15;399. doi: 10.1016/j.ccr.2019.213039. Epub 2019 Sep 4.
Abstract
Nanoscale coordination polymers (NCPs) have shown extraordinary advantages in various research areas due to their structural diversity and multifunctionality. Recently, integration of biomolecules with NCPs received extensive attention and the formed hybrid materials exhibit superior properties over the individual NCPs or biomolecules. In this review, the state-of-the-art of approaches to engineer NCPs with different types of guest biomolecules, such as amino acids, nucleic acids, enzymes and lipids are systematically introduced. Additionally, advanced applications of these biomolecule-NCP composites in the areas of sensing, catalysis, molecular imaging and therapy are thoroughly summarized. Finally, current challenges and prospects are also discussed.
摘要
纳米级配位聚合物（NCPs）由于其结构多样性和多功能性，在各个研究领域都显示出非凡的优势。最近，生物分子与NCPs的整合受到了广泛关注，所形成的杂化材料表现出比单个NCPs或生物分子更优异的性能。在这篇综述中，系统地介绍了用不同类型的客体生物分子（如氨基酸、核酸、酶和脂质）设计NCPs的最新方法。此外，还全面总结了这些生物分子-NCP复合材料在传感、催化、分子成像和治疗领域的先进应用。最后，也讨论了当前的挑战和前景。
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