Blumberg Mark S, Dooley James C, Sokoloff Greta
Department of Psychological and Brain Sciences.
Iowa Neuroscience Institute.
Curr Opin Physiol. 2020 Jun;15:14-22. doi: 10.1016/j.cophys.2019.11.002. Epub 2019 Nov 18.
Given the prevalence of sleep in early development, any satisfactory account of infant brain activity must consider what happens during sleep. Only recently, however, has it become possible to record sleep-related brain activity in newborn rodents. Using such methods in rat pups, it is now clear that sleep, more so than wake, provides a critical context for the processing of sensory input and the expression of functional connectivity throughout the sensorimotor system. In addition, sleep uniquely reveals functional activity in the developing primary motor cortex, which establishes a somatosensory map long before its role in motor control emerges. These findings will inform our understanding of the developmental processes that contribute to the nascent sense of embodiment in human infants.
鉴于睡眠在早期发育中的普遍性，任何对婴儿大脑活动的合理解释都必须考虑睡眠期间发生的情况。然而，直到最近，才有可能记录新生啮齿动物与睡眠相关的大脑活动。通过在幼鼠中使用这些方法，现在很清楚，与清醒相比，睡眠为感觉输入的处理和整个感觉运动系统中功能连接的表达提供了关键背景。此外，睡眠独特地揭示了发育中的初级运动皮层的功能活动，该皮层在其运动控制作用出现之前很久就建立了体感图谱。这些发现将有助于我们理解有助于人类婴儿新生身体感知的发育过程。
