光学相干断层扫描血管造影在雷珠单抗治疗脉络膜骨瘤合并脉络膜新生血管中的作用
The Role of Optical Coherence Tomography Angiography in Ranibizumab-Treated Choroidal Neovascularization in Choroidal Osteoma.
作者信息
Carroll William J, Zhang Yi Stephanie, Jampol Lee M, Gill Manjot K
机构信息
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
出版信息
Case Rep Ophthalmol. 2020 Jul 17;11(2):370-376. doi: 10.1159/000508032. eCollection 2020 May-Aug.
In this study, we report the initial evaluation of choroidal neovascularization (CNV) secondary to choroidal osteoma and subsequent response to anti-vascular endothelial growth factor (anti-VEGF) treatment monitored with optical coherence tomography angiography (OCT-A). A 38-year-old female presented with an initial visual acuity of 20/150 in the left eye. Clinical examination revealed a choroidal osteoma. OCT demonstrated both subretinal and intraretinal fluid. OCT-A was performed and showed CNV. A course of ten treatments with ranibizumab showed an improvement of visual acuity to 20/30-3, improvement of subretinal and intraretinal fluid, as well as attenuation of CNV. Our report demonstrates OCT-A as a useful tool for both initial evaluation of CNV and following treatment response to anti-VEGF therapy.
在本研究中，我们报告了对脉络膜骨瘤继发脉络膜新生血管（CNV）的初步评估，以及随后通过光学相干断层扫描血管造影（OCT-A）监测的抗血管内皮生长因子（抗VEGF）治疗反应。一名38岁女性左眼初始视力为20/150。临床检查发现脉络膜骨瘤。光学相干断层扫描（OCT）显示视网膜下和视网膜内均有积液。进行了OCT-A检查，显示存在CNV。使用雷珠单抗进行了十次治疗，视力提高到20/30-3，视网膜下和视网膜内积液改善，CNV也有所减轻。我们的报告表明，OCT-A是用于CNV初始评估和抗VEGF治疗反应随访的有用工具。
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