Carroll William J, Zhang Yi Stephanie, Jampol Lee M, Gill Manjot K
Department of Ophthalmology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois, USA.
Case Rep Ophthalmol. 2020 Jul 17;11(2):370-376. doi: 10.1159/000508032. eCollection 2020 May-Aug.
In this study, we report the initial evaluation of choroidal neovascularization (CNV) secondary to choroidal osteoma and subsequent response to anti-vascular endothelial growth factor (anti-VEGF) treatment monitored with optical coherence tomography angiography (OCT-A). A 38-year-old female presented with an initial visual acuity of 20/150 in the left eye. Clinical examination revealed a choroidal osteoma. OCT demonstrated both subretinal and intraretinal fluid. OCT-A was performed and showed CNV. A course of ten treatments with ranibizumab showed an improvement of visual acuity to 20/30-3, improvement of subretinal and intraretinal fluid, as well as attenuation of CNV. Our report demonstrates OCT-A as a useful tool for both initial evaluation of CNV and following treatment response to anti-VEGF therapy.
在本研究中，我们报告了对脉络膜骨瘤继发脉络膜新生血管（CNV）的初步评估，以及随后通过光学相干断层扫描血管造影（OCT-A）监测的抗血管内皮生长因子（抗VEGF）治疗反应。一名38岁女性左眼初始视力为20/150。临床检查发现脉络膜骨瘤。光学相干断层扫描（OCT）显示视网膜下和视网膜内均有积液。进行了OCT-A检查，显示存在CNV。使用雷珠单抗进行了十次治疗，视力提高到20/30-3，视网膜下和视网膜内积液改善，CNV也有所减轻。我们的报告表明，OCT-A是用于CNV初始评估和抗VEGF治疗反应随访的有用工具。
