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60 例新型冠状病毒病(COVID-19)患者的胸部计算机断层扫描(CT)表现和半定量评分:解剖与病理相结合的回顾性影像学分析。

Chest computed tomography (CT) findings and semiquantitative scoring of 60 patients with coronavirus disease 2019 (COVID-19): A retrospective imaging analysis combining anatomy and pathology.

机构信息

Department of Radiology, Dianjiang People's Hospital of Chongqing, Chongqing, China.

Department of General Surgery, Dianjiang People's Hospital of Chongqing, Chongqing, China.

出版信息

PLoS One. 2020 Sep 4;15(9):e0238760. doi: 10.1371/journal.pone.0238760. eCollection 2020.

DOI:10.1371/journal.pone.0238760
PMID:32886711
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7473568/
Abstract

In this study, we ascertained the chest CT data of 60 patients admitted to 3 hospitals in Chongqing with confirmed COVID-19. We conducted anatomical and pathological analyses to elucidate the possible reasons for the distribution, morphology, and characteristics of COVID-19 in chest CT. We also shared a semiquantitative scoring of affected lung segments, which was recommended by our local medical association. This scoring system was applied to quantify the severity of the disease. The most frequent imaging findings of COVID-19 were subpleural ground glass opacities and consolidation; there was a significant difference in semiquantitative scores between the early, progressive, and severe stages of the disease. We conclude that the chest CT findings of COVID-19 showed certain characteristics because of the anatomical features of the human body and pathological changes caused by the virus. Therefore, chest CT is a valuable tool for facilitating the diagnosis of COVID-19 and semiquantitative scoring of affected lung segments may further elucidate diagnosis and assessment of disease severity. This will assist healthcare workers in diagnosing COVID-19 and assessing disease severity, facilitate the selection of appropriate treatment options, which is important for reducing the spread of the virus, saving lives, and controlling the pandemic.

摘要

在这项研究中,我们确定了来自重庆 3 家医院的 60 名确诊 COVID-19 患者的胸部 CT 数据。我们进行了解剖学和病理学分析,以阐明 COVID-19 在胸部 CT 中的分布、形态和特征的可能原因。我们还分享了当地医学会推荐的受累肺段的半定量评分,该评分系统用于量化疾病的严重程度。COVID-19 的最常见影像学表现是胸膜下磨玻璃影和实变;疾病的早期、进展期和严重期之间的半定量评分有显著差异。我们的结论是,由于人体的解剖学特征和病毒引起的病理学变化,COVID-19 的胸部 CT 表现具有一定的特征。因此,胸部 CT 是有助于 COVID-19 诊断的有价值的工具,受累肺段的半定量评分可能进一步阐明诊断和疾病严重程度评估。这将有助于医疗保健工作者诊断 COVID-19 和评估疾病严重程度,促进选择合适的治疗方案,这对于减少病毒传播、拯救生命和控制大流行非常重要。

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