Dash Sanjay, Gupta Sandhya, Epari Venkatarao, Patra Priti Yugma
Department of Medicine, Nehru Shatabdi Central Hospital, Mahanadi Coalfields Limited, Talcher, Bhubaneswar, Odisha, India.
Department of Physiology, Institute of Medical Sciences and Sum Hospital, Siksha "O" Anusandhan Deemed to be University, Bhubaneswar, Odisha, India.
Indian J Community Med. 2020 Apr-Jun;45(2):181-183. doi: 10.4103/ijcm.IJCM_269_19. Epub 2020 Jun 2.
Coal miners working underground are likely to be at greater risk of developing Vitamin D deficiency due to reduced sunlight exposure. To date, only three studies have been reported, with no significant risk of Vitamin D deficiency among coal miners. None were conducted in the tropical region, where sunlight is ample.
The present study estimated Vitamin D levels among underground coal miners in a tropical region and determined their associated factors.
Serum calcium, 25-hydroxyvitamin D, and bone turnover markers among underground and surface workers were estimated in a matched case-control study. Binary logistic regression analysis was performed using case/control as the dependent variable to estimate odds ratios and 95% confidence intervals of variables which significantly ( < 0.1) differed among the cases and controls.
The mean Vitamin D level among both coal miners (22.12 ng/dl) and surface workers (23 ng/dl) were low. No significant difference was noted for all biochemical parameters after adjusting for other covariates except the parathyroid hormone (PTH), which was marginally higher among the surface workers.
Even in the absence of statistically significant evidence of low Vitamin D level in underground workers compared to surface workers, there was indirect evidence (of differences in PTH) to indicate that Vitamin D level is lower in underground workers probably because of poor sunlight exposure.
由于阳光照射减少，从事地下工作的煤矿工人患维生素D缺乏症的风险可能更高。迄今为止，仅报道了三项研究，煤矿工人中维生素D缺乏症的风险并不显著。这些研究均未在阳光充足的热带地区进行。
本研究估计了热带地区地下煤矿工人的维生素D水平，并确定了其相关因素。
在一项匹配病例对照研究中，对地下和地面工人的血清钙、25-羟基维生素D和骨转换标志物进行了评估。以病例/对照作为因变量进行二元逻辑回归分析，以估计病例组和对照组之间有显著差异（<0.1）的变量的比值比和95%置信区间。
煤矿工人（22.12 ng/dl）和地面工人（23 ng/dl）的维生素D平均水平均较低。在调整其他协变量后，除甲状旁腺激素（PTH）外，所有生化参数均无显著差异，地面工人的PTH略高。
即使与地面工人相比，地下工人维生素D水平低的统计学显著证据不足，但有间接证据（PTH差异）表明地下工人的维生素D水平较低，可能是因为阳光照射不足。
