Jain Uday
Anesthesiology, San Mateo Medical Center, San Mateo, USA.
Cureus. 2020 Aug 3;12(8):e9540. doi: 10.7759/cureus.9540.
The COVID-19 pandemic that first became apparent in Wuhan, China, is now infecting millions all over the world. This is a review of COVID-19's extensive effects on virtually all the organs. It causes inflammation, endotheliitis, vasoconstriction, hypercoagulability, and edema. Lymphocytopenia, elevated D-dimer, elevated fibrin degradation products (FDPs), and disseminated intravascular coagulation (DIC) are observed. Deep vein thrombosis (DVT), venous thromboembolism, pulmonary embolism (PE), systemic and pulmonary arterial thrombosis and embolism, ischemic stroke, and myocardial infarction (MI) are reported. In the heart it can cause acute coronary syndrome, congestive heart failure, myocarditis, and arrhythmias. Kidney injury is usually secondary to systemic abnormalities. Stroke occurs even in young patients. Delirium and seizures are common. Anosmia and impaired sense of taste are reported. Psychological problems are common among patients as well as providers. Stool may contain virus. Lactate dehydrogenase may be elevated. Various skin manifestations including patchy erythematous rash are reported.
最初在中国武汉出现的新型冠状病毒肺炎疫情，如今正感染着全球数百万人。本文综述了新型冠状病毒肺炎对几乎所有器官的广泛影响。它会引发炎症、内皮炎症、血管收缩、高凝状态和水肿。还会出现淋巴细胞减少、D - 二聚体升高、纤维蛋白降解产物（FDPs）升高以及弥散性血管内凝血（DIC）。有报道称出现了深静脉血栓形成（DVT）、静脉血栓栓塞、肺栓塞（PE）、全身及肺动脉血栓形成和栓塞、缺血性中风以及心肌梗死（MI）。在心脏方面，它可导致急性冠状动脉综合征、充血性心力衰竭、心肌炎和心律失常。肾损伤通常继发于全身异常。中风甚至在年轻患者中也会发生。谵妄和癫痫发作很常见。有嗅觉丧失和味觉减退的报告。患者以及医护人员中常见心理问题。粪便中可能含有病毒。乳酸脱氢酶可能升高。有各种皮肤表现的报告，包括斑片状红斑皮疹。
