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慢性微量误吸与衰弱:老年群体的关键线索?

Chronic Microaspiration and Frailty: A Geriatric Smoking Gun?

作者信息

Stewart Jonathan T, Kamath Vandan D, Jaen-Vinuales Alejandro V, Sheyner Inna

机构信息

is a Staff Geropsychiatrist, V is a Staff Speech and Language Pathologist, is a Staff Geriatrician, and is the Medical Director, Community Living Center, all at the James A. Haley Veterans' Hospital in Tampa, Florida. Jonathan Stewart is a Professor in Psychiatry and Geriatric Medicine, Alejandro Jaen-Vinuales is an Assistant Professor in Geriatric Medicine, and Inna Sheyner is an Associate Professor in Geriatric Medicine, all at the University of South Florida College of Medicine in Tampa.

出版信息

Fed Pract. 2020 Aug;37(8):384-387. doi: 10.12788/fp.0022.

DOI:10.12788/fp.0022
PMID:32908347
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7473738/
Abstract

Chronic microaspiration and diffuse aspiration bronchiolitis may account for some otherwise unexplained frailty in nursing home patients.

摘要

慢性微量误吸和弥漫性误吸性细支气管炎可能是疗养院患者中一些原本无法解释的身体虚弱的原因。

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本文引用的文献

1
Aging and Parkinson's Disease: Inflammaging, neuroinflammation and biological remodeling as key factors in pathogenesis.衰老与帕金森病:炎症衰老、神经炎症和生物重塑作为发病机制中的关键因素。
Free Radic Biol Med. 2018 Feb 1;115:80-91. doi: 10.1016/j.freeradbiomed.2017.10.379. Epub 2017 Nov 25.
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New horizons in multimorbidity in older adults.老年人多病共存的新视野。
Age Ageing. 2017 Nov 1;46(6):882-888. doi: 10.1093/ageing/afx150.
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C-Reactive Protein and Frailty in the Elderly: A Literature Review.老年人中的C反应蛋白与衰弱:文献综述
J Clin Med Res. 2017 Jun;9(6):461-465. doi: 10.14740/jocmr2959w. Epub 2017 Apr 26.
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Swallowing Disorders in Schizophrenia.精神分裂症中的吞咽障碍。
Dysphagia. 2017 Aug;32(4):467-471. doi: 10.1007/s00455-017-9802-6. Epub 2017 Apr 26.
5
Inflammatory Markers and Frailty in Long-Term Care Residents.长期护理机构居民的炎症标志物与衰弱
J Am Geriatr Soc. 2017 Aug;65(8):1777-1783. doi: 10.1111/jgs.14876. Epub 2017 Mar 21.
6
Chronic Inflammation: Accelerator of Biological Aging.慢性炎症:生物衰老的加速器。
J Gerontol A Biol Sci Med Sci. 2017 Sep 1;72(9):1218-1225. doi: 10.1093/gerona/glw240.
7
Inflammation and frailty in the elderly: A systematic review and meta-analysis.老年人的炎症与虚弱:系统评价和荟萃分析。
Ageing Res Rev. 2016 Nov;31:1-8. doi: 10.1016/j.arr.2016.08.006. Epub 2016 Aug 31.
8
An examination of factors related to aspiration and silent aspiration in older adults requiring long-term care in rural Japan.对日本农村地区需要长期护理的老年人中与误吸和隐性误吸相关因素的调查。
J Oral Rehabil. 2016 Feb;43(2):103-10. doi: 10.1111/joor.12349. Epub 2015 Oct 3.
9
Prevalence of Frailty in Nursing Homes: A Systematic Review and Meta-Analysis.养老机构中衰弱的流行率:系统评价和荟萃分析。
J Am Med Dir Assoc. 2015 Nov 1;16(11):940-5. doi: 10.1016/j.jamda.2015.06.025. Epub 2015 Aug 6.
10
Cachexia and sarcopenia: mechanisms and potential targets for intervention.恶病质与肌肉减少症:发病机制及潜在干预靶点
Curr Opin Pharmacol. 2015 Jun;22:100-6. doi: 10.1016/j.coph.2015.04.003. Epub 2015 May 14.