Panossian Alexander, Brendler Thomas
Phytomed AB, Vaxtorp, 31275 Halland, Sweden.
EuropharmaUSA, Green Bay, WI 54311, USA.
Pharmaceuticals (Basel). 2020 Sep 8;13(9):236. doi: 10.3390/ph13090236.
The aim of our review is to demonstrate the potential of herbal preparations, specifically adaptogens for prevention and treatment of respiratory infections, as well as convalescence, specifically through supporting a challenged immune system, increasing resistance to viral infection, inhibiting severe inflammatory progression, and driving effective recovery. The evidence from pre-clinical and clinical studies with , , spp., spp., , , , their combination products and melatonin suggests that adaptogens can be useful in prophylaxis and treatment of viral infections at all stages of progression of inflammation as well as in aiding recovery of the organism by (i) modulating innate and adaptive immunity, (ii) anti-inflammatory activity, (iii) detoxification and repair of oxidative stress-induced damage in compromised cells, (iv) direct antiviral effects of inhibiting viral docking or replication, and (v) improving quality of life during convalescence.
我们综述的目的是证明草药制剂，特别是适应原在预防和治疗呼吸道感染以及促进康复方面的潜力，具体是通过支持受到挑战的免疫系统、增强对病毒感染的抵抗力、抑制严重的炎症进展以及推动有效的恢复。来自对[具体植物种类1]、[具体植物种类2]、[具体植物种类3]及其组合产品以及褪黑素进行的临床前和临床研究的证据表明，适应原在炎症进展的各个阶段对病毒感染的预防和治疗以及帮助机体恢复方面可能是有用的，具体方式包括：（i）调节固有免疫和适应性免疫；（ii）抗炎活性；（iii）对受损细胞中氧化应激诱导的损伤进行解毒和修复；（iv）抑制病毒对接或复制的直接抗病毒作用；以及（v）在康复期间改善生活质量。
