Gómez-Martinez Jesús, López-Pintor Elsa, Lumbreras Blanca
Pharmacy Jesús C. Gómez Martínez, Barcelona 08041, Spain.
Department of Engineering, Area of Pharmacy and Pharmaceutical Technologies, Miguel Hernández University, Alicante 03550, Spain.
Patient Prefer Adherence. 2020 Aug 24;14:1501-1511. doi: 10.2147/PPA.S260404. eCollection 2020.
The aim of this study was to evaluate the provision of a professional pharmaceutical patient-centered model in a weight management program and optimization of the medication in a Spanish community pharmacy.
This was a single-group intervention study with a mean follow-up period of 8.2 months (sd 2.3). Patients ≥18 years old seeking to lose weight or improve eating habits were recruited. On the first visit, the pharmacist collected patients' sociodemographic and anthropometric variables, dietary history and lifestyle habits, biochemical measurements and other clinical and therapeutic data. The intervention was based on the Spanish Society of Community Pharmacy recommendations for diet and exercise and for pharmacotherapy management. The follow-up included a two-month visit and a final visit.
A total of 330 patients were included (80% women; mean age 51.3 years old (sd 15.3)). A statistically significant reduction in anthropometric measurements (weight, BMI, and waist circumference) and a statistically significant increase in the number of patients with normal cholesterol and LDL-cholesterol (p<0.001) were observed at two-month visit compared with first visit (p<0.001). The number of patients with normal triglyceride levels at final visit compared with first visit also increased significantly (p=0.04). A total of 186 (56.4%) patients had drug-related problems at first visit and 31 (9.4%) patients at two-month visit.
The implementation of a patient-centered weight management model had a positive impact on the improvement of anthropometric, clinical and therapeutic parameters.
本研究旨在评估在西班牙一家社区药房的体重管理项目中提供以患者为中心的专业药学模式以及优化药物治疗的情况。
这是一项单组干预研究，平均随访期为8.2个月（标准差2.3）。招募年龄≥18岁、寻求减肥或改善饮食习惯的患者。首次就诊时，药剂师收集患者的社会人口统计学和人体测量学变量、饮食史和生活习惯、生化指标以及其他临床和治疗数据。干预措施基于西班牙社区药房协会关于饮食、运动和药物治疗管理的建议。随访包括为期两个月的复诊和末次复诊。
共纳入330例患者（80%为女性；平均年龄51.3岁（标准差15.3））。与首次就诊相比，在两个月复诊时观察到人体测量指标（体重、体重指数和腰围）有统计学意义的降低，胆固醇和低密度脂蛋白胆固醇正常的患者数量有统计学意义的增加（p<0.001）。与首次就诊相比，末次复诊时甘油三酯水平正常的患者数量也显著增加（p=0.04）。首次就诊时共有186例（56.4%）患者存在药物相关问题，两个月复诊时为31例（9.4%）。
实施以患者为中心的体重管理模式对改善人体测量、临床和治疗参数有积极影响。
