Aslam Adeel, Gajdács Márió, Zin Che Suraya, Ab Rahman Norny Syafinaz, Ahmed Syed Imran, Zafar Muhammad Zeeshan, Jamshed Shazia
Department of Pharmacy Practice, Kulliyyah of Pharmacy, International Islamic University Malaysia, Kuantan 25200, Malaysia.
Department of Pharmacodynamics and Biopharmacy, Faculty of Pharmacy, University of Szeged, 6720 Szeged, Hungary.
Antibiotics (Basel). 2020 Sep 12;9(9):597. doi: 10.3390/antibiotics9090597.
The current scoping review is an attempt to explore the key reasons, determinants, patterns and prevalence related to self-medication with antibiotics (SMA) among the lay public. An online search was conducted using Google Scholar, Science Direct, ProQuest and PubMed. A two-phase mapping approach was used. In the first phase, studies were screened. In the second phase, the data were extracted from selected studies followed by the assessment of data quality. A total of 24 studies were included; 20 were cross-sectional, 3 were qualitative and one was observational. The most common indications were flu, cough, common colds, sore throat, diarrhea, toothache and fever. The most common determinants reported were past good experience and suggestions from friends or relatives. The use of SMA was observed to be more frequent in younger aged individuals belonging to low- or middle-income groups. The prevalence rate was reported to be high among the South Asian lay public and may be a major contributor to antibiotic resistance. In conclusion, this scoping review identifies a need for education campaigns and mass media campaigns to strengthen lay public awareness about the side effects and risks associated with SMA. In addition to this, there is a need to implement strict policies by government agencies to restrict over the counter availability of antibiotics.
当前的范围综述旨在探究普通公众中与抗生素自我药疗（SMA）相关的关键原因、决定因素、模式及流行情况。通过谷歌学术、科学Direct、ProQuest和PubMed进行了在线搜索。采用了两阶段映射方法。在第一阶段，对研究进行筛选。在第二阶段，从选定的研究中提取数据，随后评估数据质量。共纳入24项研究；20项为横断面研究，3项为定性研究，1项为观察性研究。最常见的适应证为流感、咳嗽、普通感冒、喉咙痛、腹泻、牙痛和发热。报告的最常见决定因素为过去的良好经验以及朋友或亲属的建议。观察到SMA在低收入或中等收入群体的年轻个体中使用更为频繁。据报道，南亚普通公众中的患病率较高，可能是抗生素耐药性的主要促成因素。总之，本范围综述确定需要开展教育活动和大众媒体宣传活动，以增强普通公众对SMA相关副作用和风险的认识。除此之外，政府机构需要实施严格政策，限制抗生素的非处方可得性。
