Ngu Roland Cheofor, Feteh Vitalis Fambombi, Kika Belmond Tse, F Emade Ketchemen Nerice, Ayeah Chia Mark, Chifor Theresia, Njim Tsi, Fankem Alvine Manuela, Yengo Franklin Kwenti Fai
Medical Doctors Research Group (MDRG), Douala 15161, Cameroon.
Mboppi Baptist Hospital Douala, Douala 15161, Cameroon.
Diseases. 2018 Jun 8;6(2):49. doi: 10.3390/diseases6020049.
Antibiotic self-medication in patients with respiratory tract infections (RTI) is increasing globally and has been reported to be one of the prime contributors to antimicrobial resistance (AMR). Our study aims to provide data on the prevalence of antibiotic self-medication and identify the factors contributing to self-medication in adult patients with respiratory tract infection in an urban setting in Cameroon. This was cross-sectional study carried out at Mboppi Baptist Hospital, Douala, Cameroon. A validated structured questionnaire was administered to 308 consenting participants with diagnosed RTIs, to collect data on socio-demographic characteristics and history of antibiotic self-medication. Significance was set at a -value < 0.05. The prevalence of antibiotic self-medication amongst individuals with RTIs was 41.9% (95% CI 36.5% to 47.5%). Patients with a history of pulmonary tuberculosis (TB) were significantly less likely to self-medicate with antibiotics (-value = 0.043). The most common source of antibiotic self-medication was pharmacies (62%) and Cotrimoxazole and Amoxicillin were the most commonly used antibiotics (38.8% (50), 26.4% (34), respectively). Self-medication with antibiotics in adult patients with RTIs is common in Cameroon. Control of the use of antibiotics, organisation of medication stewardship programs, and education of the general population on the adverse consequences of antibiotic self-medication are required.
在全球范围内，呼吸道感染（RTI）患者的抗生素自我药疗情况呈上升趋势，据报道，这是导致抗菌药物耐药性（AMR）的主要因素之一。我们的研究旨在提供喀麦隆城市地区成年呼吸道感染患者抗生素自我药疗的患病率数据，并确定导致自我药疗的因素。这是在喀麦隆杜阿拉的姆博皮浸信会医院进行的一项横断面研究。对308名确诊为RTI的同意参与研究的参与者进行了一份经过验证的结构化问卷调查，以收集社会人口学特征和抗生素自我药疗史的数据。显著性设定为P值<0.05。RTI患者中抗生素自我药疗的患病率为41.9%（95%CI 36.5%至47.5%）。有肺结核（TB）病史的患者使用抗生素自我药疗的可能性显著降低（P值=0.043）。抗生素自我药疗最常见的来源是药店（62%），最常用的抗生素是复方新诺明和阿莫西林（分别为38.8%（50例）、26.4%（34例））。在喀麦隆，成年RTI患者的抗生素自我药疗很常见。需要控制抗生素的使用、组织用药管理计划，并对普通人群进行抗生素自我药疗不良后果的教育。
