Kim Seon-Rye, Nam Seoul-Hee
Department of Pharmacy, College of Pharmacy, Kangwon National University, Chuncheon-si 24341, Korea.
Department of Dental Hygiene, College of Health Science, Kangwon National University, Samcheok-si 25945, Korea.
Healthcare (Basel). 2020 Sep 12;8(3):337. doi: 10.3390/healthcare8030337.
Although the correlation between periodontal condition and hyperlipidemia was shown by previous researches, it remains disputed. This study was based on data from the seventh Korea National Health and Nutrition Examination Survey 2016-2018. Data included 14,068 subjects' demographic characteristics, total cholesterol levels, triglyceride levels, and periodontal conditions. We analyzed the correlation between periodontal disease and blood lipid levels using complex-sample chi square tests and complex-sample logistic regression. The results of chi square tests showed a significant difference in demographic characteristics according to total cholesterol level and triglyceride level. The results of logistic regression, adjusted for the subjects' demographic characteristics such as age, gender, house income, marital status, home ownership, number of persons living together, health insurance coverage, and economic activity, showed that prevalence of periodontal disease was 1.048-fold (confidence interval (CI) 0.827-1.133) higher in the high-total-cholesterol group and 1.499-fold (CI 1.576-1.983) higher in high-triglyceride group. We found that not high total cholesterol but high triglyceride level was connected with periodontal disease. Therefore, management of triglyceride level could be a possible precaution of periodontal disease.
尽管先前的研究表明牙周状况与高脂血症之间存在关联,但这一观点仍存在争议。本研究基于2016 - 2018年第七次韩国国家健康与营养检查调查的数据。数据包括14,068名受试者的人口统计学特征、总胆固醇水平、甘油三酯水平和牙周状况。我们使用复杂样本卡方检验和复杂样本逻辑回归分析了牙周疾病与血脂水平之间的相关性。卡方检验结果显示,根据总胆固醇水平和甘油三酯水平,人口统计学特征存在显著差异。逻辑回归结果在对受试者的年龄、性别、家庭收入、婚姻状况、住房所有权、共同居住人数、健康保险覆盖范围和经济活动等人口统计学特征进行调整后表明,高总胆固醇组的牙周疾病患病率高1.048倍(置信区间(CI)0.827 - 1.133),高甘油三酯组的牙周疾病患病率高1.499倍(CI 1.576 - 1.983)。我们发现,与牙周疾病相关的不是高总胆固醇,而是高甘油三酯水平。因此,控制甘油三酯水平可能是预防牙周疾病的一种可行措施。