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Am J Physiol Gastrointest Liver Physiol. 2020 May 1;318(5):G889-G906. doi: 10.1152/ajpgi.00161.2019. Epub 2020 Mar 9.
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Critical Appraisal of Bidirectional Relationship between Periodontitis and Hyperlipidemia.牙周炎与高脂血症双向关系的批判性评估
J Int Soc Prev Community Dent. 2019 Mar-Apr;9(2):112-118. doi: 10.4103/jispcd.JISPCD_316_18. Epub 2019 Apr 12.
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Relationship between the burden of major periodontal bacteria and serum lipid profile in a cross-sectional Japanese study.一项日本横断面研究中主要牙周细菌负荷与血清脂质谱之间的关系。
BMC Oral Health. 2018 May 4;18(1):77. doi: 10.1186/s12903-018-0536-0.
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Serum lipid levels in patients with periodontal disease: A meta-analysis and meta-regression.牙周病患者的血清脂质水平:荟萃分析和荟萃回归。
J Clin Periodontol. 2017 Dec;44(12):1192-1207. doi: 10.1111/jcpe.12792. Epub 2017 Nov 17.
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Prevention and control of dental caries and periodontal diseases at individual and population level: consensus report of group 3 of joint EFP/ORCA workshop on the boundaries between caries and periodontal diseases.个体和人群层面的龋齿和牙周病的预防和控制:EFP/ORCA 工作组关于龋齿和牙周病之间界限的第 3 组联合研讨会的共识报告。
J Clin Periodontol. 2017 Mar;44 Suppl 18:S85-S93. doi: 10.1111/jcpe.12687.
6
Optimal cutoff of the triglyceride to high-density lipoprotein cholesterol  ratio to detect cardiovascular risk factors among Han adults in Xinjiang.新疆汉族成年人中甘油三酯与高密度脂蛋白胆固醇比值用于检测心血管危险因素的最佳临界值
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7
Association of periodontal and cardiovascular diseases: South-Asian studies 2001-2012.牙周病与心血管疾病的关联:2001 - 2012年南亚地区研究
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8
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9
Relationship between obesity and oral diseases.肥胖与口腔疾病之间的关系。
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韩国成年人牙周疾病与甘油三酯及总胆固醇水平之间的关联

Association between Periodontal Disease and Levels of Triglyceride and Total Cholesterol among Korean Adults.

作者信息

Kim Seon-Rye, Nam Seoul-Hee

机构信息

Department of Pharmacy, College of Pharmacy, Kangwon National University, Chuncheon-si 24341, Korea.

Department of Dental Hygiene, College of Health Science, Kangwon National University, Samcheok-si 25945, Korea.

出版信息

Healthcare (Basel). 2020 Sep 12;8(3):337. doi: 10.3390/healthcare8030337.

DOI:10.3390/healthcare8030337
PMID:32932647
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC7551387/
Abstract

Although the correlation between periodontal condition and hyperlipidemia was shown by previous researches, it remains disputed. This study was based on data from the seventh Korea National Health and Nutrition Examination Survey 2016-2018. Data included 14,068 subjects' demographic characteristics, total cholesterol levels, triglyceride levels, and periodontal conditions. We analyzed the correlation between periodontal disease and blood lipid levels using complex-sample chi square tests and complex-sample logistic regression. The results of chi square tests showed a significant difference in demographic characteristics according to total cholesterol level and triglyceride level. The results of logistic regression, adjusted for the subjects' demographic characteristics such as age, gender, house income, marital status, home ownership, number of persons living together, health insurance coverage, and economic activity, showed that prevalence of periodontal disease was 1.048-fold (confidence interval (CI) 0.827-1.133) higher in the high-total-cholesterol group and 1.499-fold (CI 1.576-1.983) higher in high-triglyceride group. We found that not high total cholesterol but high triglyceride level was connected with periodontal disease. Therefore, management of triglyceride level could be a possible precaution of periodontal disease.

摘要

尽管先前的研究表明牙周状况与高脂血症之间存在关联,但这一观点仍存在争议。本研究基于2016 - 2018年第七次韩国国家健康与营养检查调查的数据。数据包括14,068名受试者的人口统计学特征、总胆固醇水平、甘油三酯水平和牙周状况。我们使用复杂样本卡方检验和复杂样本逻辑回归分析了牙周疾病与血脂水平之间的相关性。卡方检验结果显示,根据总胆固醇水平和甘油三酯水平,人口统计学特征存在显著差异。逻辑回归结果在对受试者的年龄、性别、家庭收入、婚姻状况、住房所有权、共同居住人数、健康保险覆盖范围和经济活动等人口统计学特征进行调整后表明,高总胆固醇组的牙周疾病患病率高1.048倍(置信区间(CI)0.827 - 1.133),高甘油三酯组的牙周疾病患病率高1.499倍(CI 1.576 - 1.983)。我们发现,与牙周疾病相关的不是高总胆固醇,而是高甘油三酯水平。因此,控制甘油三酯水平可能是预防牙周疾病的一种可行措施。