Hoyle C F, Boughton B J, Hayhoe F G
Department of Haematological Medicine, University Clinical School, Cambridge, England.
Cancer Genet Cytogenet. 1988 Aug;34(1):29-32. doi: 10.1016/0165-4608(88)90164-1.
Two cases of acute myeloid leukemia (FAB M1 and M2) with trisomy 4 are described. Morphologic abnormalities were confined to the granulocytic monocytic lineage with no evidence of erythroid or megakaryocytic involvement. One of the cases, who also had trisomy 13, presented initially with skin infiltration without bone marrow involvement.
描述了两例伴有4号染色体三体的急性髓系白血病(FAB M1和M2)。形态学异常局限于粒单核细胞系,无红系或巨核系受累证据。其中一例还伴有13号染色体三体,最初表现为皮肤浸润,无骨髓受累。