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线性无阈假说问题关乎政治与经济,而非安全。

The LNT Issue Is About Politics and Economics, Not Safety.

作者信息

Cuttler Jerry M

机构信息

Cuttler & Associates Inc, Vaughan, Ontario, Canada.

出版信息

Dose Response. 2020 Sep 2;18(3):1559325820949066. doi: 10.1177/1559325820949066. eCollection 2020 Jul-Sep.

Abstract

The Sykes commentary advocates "a more sensible, graded approach for protection from low dose ionizing radiation" until the LNT dose-response issue is resolved. It urges scientists to stop criticizing the LNT model that links radiation to a risk of cancer and accept regulatory use of the threshold model to "protect" people, but with higher limits. It fails to mention the 120-year history of successful low-dose treatments of a wide variety of serious diseases, including cancers. The commentary ignores published evidence of a threshold at 1.1 Gy for radiogenic leukemia and a dose-rate threshold at about 0.6 Gy per year for lifespan shortening. LNT came from politicized science, replete with scientific misconduct and conflict of interest. Its acceptance created a false cancer scare that was likely intended to stop atomic bomb testing, but it has severely damaged human welfare. Many vitally important low-dose therapies were discarded when the radiation scare was disseminated in 1956. The rapid growth of nuclear energy ended with the media-inflamed public panic after the Three Mile Island accident in 1979. Extreme implementation of the precautionary principle made it uneconomic. Availability of a low-dose therapy for lung inflammation could have dramatically decreased the impact of the COVID-19 pandemic.

摘要

赛克斯的评论主张,在低剂量辐射致癌风险模型(LNT)的剂量反应问题得到解决之前,应采取“更合理、分级的低剂量电离辐射防护方法”。该评论敦促科学家停止批评将辐射与癌症风险联系起来的LNT模型,并接受使用阈值模型进行监管以“保护”人们,但设定的限值更高。它没有提及120年来成功使用低剂量疗法治疗包括癌症在内的各种严重疾病的历史。该评论忽略了已发表的关于放射性白血病阈值为1.1戈瑞以及寿命缩短的剂量率阈值约为每年0.6戈瑞的证据。LNT源于政治化的科学,充斥着科学不端行为和利益冲突。对它的接受制造了一场虚假的癌症恐慌,其目的可能是为了阻止原子弹试验,但它严重损害了人类福祉。1956年传播辐射恐慌时,许多至关重要的低剂量疗法被摒弃。1979年三里岛事故后,媒体煽动公众恐慌,核能的快速发展就此终结。预防性原则的极端实施使其变得不经济。一种针对肺部炎症的低剂量疗法本可大幅降低新冠疫情的影响。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4045/7476350/6c439b97afc7/10.1177_1559325820949066-fig1.jpg

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